FlyBase Allele Report: Dmel\rho[ve-1]

General Information

Symbol

Dmel\rho^ve-1

Species

D. melanogaster

Name

FlyBase ID

FBal0017855

Feature type

allele

Associated gene

Dmel\rho

Associated Insertion(s)

Carried in Construct

Also Known As

rho^ve, ve¹, rho^ve1

Key Links

Allele class

loss of function allele

Mutagen

spontaneous

Nature of the Allele

Allele class

loss of function allele

(Milan et al., 1997, Sawamoto et al., 1994, Sturtevant et al., 1993)

Mutagen

spontaneous

(Lindsley and Zimm, 1992)

Progenitor genotype

Cytology

Description

Mutation within the promoter region.

(Sturtevant et al., 1993)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Yano et al., 2005, Kotarski et al., 1998, de Celis, 1997, Lindsley and Zimm, 1992)

visible

(Nagel et al., 2016, Rendina et al., 2010)

visible | dominant

(Rougeot et al., 2013)

visible | recessive

(Guichard et al., 1999, Roch et al., 1998, Sturtevant et al., 1993)

Phenotype Manifest In

segment border muscle cell | ectopic

(Bidet et al., 2003)

wing vein

(Tjota et al., 2011, Ralston and Blair, 2005, de Celis, 1997, Sturtevant et al., 1993, Lindsley and Zimm, 1992)

wing vein | adult stage

(Nagel et al., 2016)

wing vein | distal

(de Celis, 1997)

wing vein L1

(Murray et al., 1995)

wing vein L2

(Marenda et al., 2004, Murray et al., 1995, Sawamoto et al., 1994)

wing vein L3

(Li et al., 2007, Ragab et al., 2006, Yano et al., 2005, Marenda et al., 2004, Gallio et al., 2002, Murray et al., 1995, Sawamoto et al., 1994)

wing vein L3 | distal

(Rendina et al., 2010)

wing vein L4

(Rendina et al., 2010, Li et al., 2007, Ragab et al., 2006, Yano et al., 2005, Marenda et al., 2004, Gallio et al., 2002, Guichard et al., 1999, Murray et al., 1995, Sawamoto et al., 1994)

wing vein L5

(Rougeot et al., 2013, Tjota et al., 2011, Rendina et al., 2010, Li et al., 2007, Ragab et al., 2006, Yano et al., 2005, Marenda et al., 2004, Gallio et al., 2002, Guichard et al., 1999, Murray et al., 1995, Sawamoto et al., 1994)

wing vein L5 (with Df(3L)ru-22)

(Tjota et al., 2011)

wing vein L6

(Murray et al., 1995)

Detailed Description

Statement

Reference

The rho^ve-1 mutant phenotype is characterized by distal gaps in the longitudinal veins.

(Nagel et al., 2016)

13.2% of heterozygous females have a truncated L5 wing vein.

(Rougeot et al., 2013)

Homozygous rho^ve-1 flies exhibit truncated wing veins.

(Tjota et al., 2011)

Homozygotes lack the distal portion of wing vein L3 and lack most of the L4 and L5 wing veins.

(Rendina et al., 2010)

Homozygous rho^ve-1 mutants show loss of partial L3, L4 and L5 and weakened L2-L4 M veins, whereas heterozygous rho^ve-1 exhibit only a weakened distal portion of L5 vein.

(Li et al., 2007)

rho^ve-1 flies show a partial loss of wing veins L3, L4 and L5.

(Ragab et al., 2006)

The initial development of most veins in the wing is disrupted in rho^ve-1 mutants.

(Ralston and Blair, 2005)

rho^ve-1 mutants are viable, exhibiting partial loss of L3-L5 wing veins.

(Yano et al., 2005)

Homozygotes show incomplete wing veins L2, L3, L4 and L5.

(Marenda et al., 2004)

Mutant embryos show duplication of the segmental border muscle and a complete loss of lateral adult muscle precursors.

(Bidet et al., 2003)

rho^ve-1 mutant flies show loss of the distal ends of wing veins, particularly L3, L4 and L5.

(Gallio et al., 2002)

The interactions between rho^ve-1/rho^ve-1 and emc^D or emc¹/emc¹¹ are additive. The interactions between rho^ve-1/rho⁹ and emc^D or emc¹/emc¹¹ are additive. emc¹ clones in rho^ve-1 vn¹ wings differentiate as veins in positions possibly corresponding to those of wild-type veins. Vein differentiation in these clones frequently fails in distal regions of veins.

(Baonza and Garcia-Bellido, 1999)

In a e¹, rho^ve-1 double mutant, in which all of the longitudinal veins are truncated or eliminated, ectopic melanin only develops in proximal areas that truncate before reaching the margin.

(True et al., 1999)

Germline clones fail to rescue the female sterile phenotype of Fs(3)Apc.

(Sapir et al., 1998)

Homozygotes lack the distal ends of all longitudinal wing veins.

(de Celis, 1997)

Wings lack the longitudinal veins.

(Murray et al., 1995)

rho^ve-1 supresses the vein defects of bs mutations although L2 to L5 remain truncated distally.

(Fristrom et al., 1994)

Wings have shortened longitudinal veins that do not reach the wing margin.

(Sawamoto et al., 1994)

Lack distal segments of wing veins especially veins L4 and L5. Homozygous phenotype is strongly suppressed by heterozygous rho^Wk.

(Sturtevant et al., 1993)

Wing veins do not reach margins.

(Lindsley and Zimm, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

rho^ve-1 has visible phenotype, enhanceable by CycG^HR7

(Nagel et al., 2016)

rho^ve-1 has visible phenotype, enhanceable by vn¹

(Nagel et al., 2016)

rho^ve-1 has visible phenotype, enhanceable by aos^hs.PSa

(Sawamoto et al., 1994)

Suppressed by

Statement

Reference

rho⁹/rho^ve-1, vn^M2/vn¹ has visible phenotype, suppressible by bs⁰³²⁶⁷/bs²

(Roch et al., 1998)

NOT suppressed by

Statement

Reference

rho^ve-1 has visible phenotype, non-suppressible by Bap170^hfl1/Bap170[+]

(Rendina et al., 2010)

rho^ve-1 has viable phenotype, non-suppressible by frc^RY34/frc[+]

(Yano et al., 2005)

Enhancer of

Statement

Reference

rho^ve-1/rho[+] is an enhancer of abnormal size | adult stage phenotype of sl²

(Murillo-Maldonado et al., 2011)

rho^ve-1/rho[+] is an enhancer of visible | dominant phenotype of sog^EP7

(Araujo et al., 2003)

rho^ve-1/rho[+] is an enhancer of visible | dominant phenotype of sog^EP11

(Araujo et al., 2003)

rho^ve-1 is an enhancer of visible phenotype of aos^hs.PSa

(Sawamoto et al., 1994)

Suppressor of

Statement

Reference

vn[+], rho^ve-1, vn¹, rho[+] is a suppressor of visible phenotype of Chmp1^GD11219, Scer\GAL4^Bx-MS1096

(Valentine et al., 2014)

rho^ve-1/rho[+] is a suppressor of increased cell number | adult stage phenotype of sl²

(Murillo-Maldonado et al., 2011)

rho^ve-1/rho[+] is a suppressor of visible phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

rho^ve-1/rho^ve-1 is a suppressor | partially of visible phenotype of H^C2.UAS, Scer\GAL4^en-e16E

(Johannes and Preiss, 2002)

rho^ve-1/rho[+] is a suppressor of visible | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

rho^ve-1/rho[+] is a suppressor of visible | recessive phenotype of px¹

(Wessendorf et al., 1992)

rho^ve-1/rho^ve-1 is a suppressor of visible | recessive phenotype of px⁷²

(Wessendorf et al., 1992)

NOT Suppressor of

Statement

Reference

rho^ve-1/rho[+] is a non-suppressor of visible phenotype of Chmp1^GD11219, Scer\GAL4^Bx-MS1096

(Valentine et al., 2014)

Other

Statement

Reference

pk³⁰, rho^ve-1, vn¹ has visible phenotype

(Hogan et al., 2011)

pk³⁰, rho^ve-1, vn¹ has abnormal planar polarity phenotype

(Hogan et al., 2011)

rho^ve-1, vn¹ has visible | recessive phenotype

(Martin-Blanco et al., 1999, Milan et al., 1997)

rho⁹/rho^ve-1, vn^M2/vn¹ has visible phenotype

(Roch et al., 1998)

rho^ve-1, vn¹ has visible phenotype

(Wolfgang et al., 1996)

Phenotype Manifest In

Enhanced by

Statement

Reference

rho^ve-1 has wing vein | adult stage phenotype, enhanceable by CycG^HR7

(Nagel et al., 2016)

rho^ve-1 has wing vein L4 | adult stage phenotype, enhanceable by vn¹

(Nagel et al., 2016)

rho^ve-1 has wing vein L5 phenotype, enhanceable by Df(2R)ED3921

(Ragab et al., 2006)

rho^ve-1 has wing vein L5 phenotype, enhanceable by brm²

(Marenda et al., 2004)

rho^ve-1 has wing vein L3 phenotype, enhanceable by Pc⁴

(Marenda et al., 2004)

rho^ve-1 has wing vein phenotype, enhanceable by Egfr^t1/Egfr^f1

(Guichard et al., 1999)

rho^ve-1 has wing vein phenotype, enhanceable by aos^hs.PSa

(Sawamoto et al., 1994)

NOT Enhanced by

Statement

Reference

rho^ve-1 has wing vein L3 phenotype, non-enhanceable by Df(2R)ED3921

(Ragab et al., 2006)

rho^ve-1 has wing vein L4 phenotype, non-enhanceable by Df(2R)ED3921

(Ragab et al., 2006)

rho^ve-1 has phenotype, non-enhanceable by ast^K6

(Kotarski et al., 1998)

Suppressed by

Statement

Reference

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible by Rab5²

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible | partially by Rbsn-5^40-3

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible | partially by Hrs^v28

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible | partially by Eps-15^e75

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible by Vps28^B9

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible by Vps25^A3

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible by Vps20^I3

(Tjota et al., 2011)

Df(3L)ru-22/rho^ve-1 has wing vein L5 phenotype, suppressible by shrb^G5

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by kst¹

(Tjota et al., 2011)

rho^ve-1 has wing vein L2 phenotype, suppressible by kst¹

(Tjota et al., 2011)

rho^ve-1 has wing vein L3 phenotype, suppressible by kst¹

(Tjota et al., 2011)

rho^ve-1 has wing vein L4 phenotype, suppressible by kst¹

(Tjota et al., 2011)

rho^ve-1 has wing vein phenotype, suppressible by AnxB9^RNAi.UAS/Scer\GAL4^Bx-MS1096

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Rab5²

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Rbsn-5^40-3

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Hrs^v28

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Eps-15^e75

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Vps28^B9

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Vps25^A3

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by Vps20^I3

(Tjota et al., 2011)

rho^ve-1 has wing vein L5 phenotype, suppressible by shrb^G5

(Tjota et al., 2011)

rho^ve-1, vn¹ has wing vein phenotype, suppressible | partially by ash2^S112411/ash2^S112411

(Angulo et al., 2004)

brm², rho^ve-1 has wing vein L5 phenotype, suppressible by Snr1^E1

(Marenda et al., 2004)

rho^ve-1 has wing vein L5 phenotype, suppressible by Snr1^R3/Snr1^E1

(Marenda et al., 2004)

rho^ve-1 has wing vein L4 phenotype, suppressible by Pstu\aarA^UAS.cGa/Scer\GAL4^Bx-MS1096

(Gallio et al., 2002)

rho^ve-1 has wing vein L5 phenotype, suppressible by Pstu\aarA^UAS.cGa/Scer\GAL4^Bx-MS1096

(Gallio et al., 2002)

rho^ve-1 has wing vein L3 phenotype, suppressible by Pstu\aarA^UAS.cGa/Scer\GAL4^Bx-MS1096

(Gallio et al., 2002)

rho⁹/rho^ve-1, vn^M2/vn¹ has wing vein phenotype, suppressible by bs⁰³²⁶⁷/bs²

(Roch et al., 1998)

rho^ve-1, vn¹ has wing vein phenotype, suppressible by dpp^UAS.cSa/Scer\GAL4^C-580

(de Celis, 1997)

rho^ve-1 has phenotype, suppressible by bs^Px

(Sturtevant and Bier, 1995)

rho^ve-1 has wing vein phenotype, suppressible by bs^ba

(Sturtevant and Bier, 1995)

rho^ve-1 has wing vein phenotype, suppressible by bs¹¹

(Sturtevant and Bier, 1995)

rho^ve-1 has wing vein phenotype, suppressible by bs²

(Sturtevant and Bier, 1995)

rho^ve-1 has phenotype, suppressible by gra¹

(Lindsley and Zimm, 1992)

NOT suppressed by

Statement

Reference

rho^ve-1 has wing vein L4 phenotype, non-suppressible by Bap170^hfl1/Bap170[+]

(Rendina et al., 2010)

rho^ve-1 has wing vein L5 phenotype, non-suppressible by Bap170^hfl1/Bap170[+]

(Rendina et al., 2010)

rho^ve-1 has wing vein L3 | distal phenotype, non-suppressible by Bap170^hfl1/Bap170[+]

(Rendina et al., 2010)

rho^ve-1, vn¹ has wing vein phenotype, non-suppressible by osa^UAS.cCa/Scer\GAL4^salm-459.2

(Terriente-Félix and de Celis, 2009)

rho^ve-1 has wing vein L3 phenotype, non-suppressible by frc^RY34/frc[+]

(Yano et al., 2005)

rho^ve-1 has wing vein L4 phenotype, non-suppressible by frc^RY34/frc[+]

(Yano et al., 2005)

rho^ve-1 has wing vein L5 phenotype, non-suppressible by frc^RY34/frc[+]

(Yano et al., 2005)

Enhancer of

Statement

Reference

rho^ve-1/rho[+] is an enhancer of wing blade phenotype of sl²

(Murillo-Maldonado et al., 2011)

rho^ve-1/rho[+] is an enhancer of wing vein | ectopic phenotype of sl²

(Murillo-Maldonado et al., 2011)

rho^ve-1/rho[+] is an enhancer of wing vein phenotype of sog^EP11

(Araujo et al., 2003)

rho^ve-1/rho[+] is an enhancer of wing vein phenotype of sog^EP7

(Araujo et al., 2003)

rho^ve-1 is an enhancer of wing vein phenotype of aos^hs.PSa

(Sawamoto et al., 1994)

NOT Enhancer of

Statement

Reference

rho^ve-1/vn¹ is a non-enhancer of wing vein | ectopic phenotype of bwk^Δ11, cic^D49

(Roch et al., 2002)

rho^ve-1 is a non-enhancer of wing disc phenotype of ft^k07918

(Garoia et al., 2000)

Suppressor of

Statement

Reference

vn[+], rho^ve-1, vn¹, rho[+] is a suppressor of wing vein phenotype of Chmp1^GD11219, Scer\GAL4^Bx-MS1096

(Valentine et al., 2014)

rho^ve-1/rho[+] is a suppressor of photoreceptor cell R7 | adult stage phenotype of sl²

(Murillo-Maldonado et al., 2011)

rho^ve-1/Scer\GAL4^e22c is a suppressor | partially of wing vein L4 phenotype of Scer\GAL4^e22c, Ubqn^RNAi.Ex2.UAS

(Li et al., 2007)

rho^ve-1/Scer\GAL4^e22c is a suppressor | partially of wing vein L5 phenotype of Scer\GAL4^e22c, Ubqn^RNAi.Ex2.UAS

(Li et al., 2007)

rho^ve-1/Scer\GAL4^e22c is a suppressor | partially of wing vein L3 phenotype of Scer\GAL4^e22c, Ubqn^RNAi.Ex2.UAS

(Li et al., 2007)

rho^ve-1/Scer\GAL4^e22c is a suppressor | partially of posterior crossvein phenotype of Scer\GAL4^e22c, Ubqn^RNAi.Ex2.UAS

(Li et al., 2007)

rho^ve-1/rho[+] is a suppressor of wing vein | ectopic phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

rho^ve-1/rho^ve-1 is a suppressor of wing vein | ectopic phenotype of Snr1^R3/Snr1^E1

(Marenda et al., 2004)

rho^ve-1/rho^ve-1 is a suppressor of wing vein | ectopic phenotype of H^C2.UAS, Scer\GAL4^en-e16E

(Johannes and Preiss, 2002)

rho^ve-1/rho^ve-1 is a suppressor of wing vein | ectopic phenotype of H^UAS.cMa, Scer\GAL4^en-e16E

(Johannes and Preiss, 2002)

rho^ve-1/rho[+] is a suppressor of wing vein | ectopic | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

rho^ve-1/rho[+] is a suppressor of wing | heat sensitive phenotype of H^C2.hs

(Johannes and Preiss, 2002)

rho^ve-1 is a suppressor of wing vein phenotype of tkv¹/tkv⁸

(de Celis, 1997)

rho^ve-1 is a suppressor of wing vein | ectopic phenotype of bs^A48

(Fristrom et al., 1994)

rho^ve-1 is a suppressor of wing phenotype of bs^A48

(Fristrom et al., 1994)

rho^ve-1/rho[+] is a suppressor of wing phenotype of px¹

(Wessendorf et al., 1992)

rho^ve-1/rho^ve-1 is a suppressor of wing phenotype of px⁷²

(Wessendorf et al., 1992)

NOT Suppressor of

Statement

Reference

rho^ve-1/rho[+] is a non-suppressor of wing vein phenotype of Chmp1^GD11219, Scer\GAL4^Bx-MS1096

(Valentine et al., 2014)

rho^ve-1/rho^ve-1 is a non-suppressor of wing & microchaeta | ectopic phenotype of H^C2.UAS, Scer\GAL4^en-e16E

(Johannes and Preiss, 2002)

rho^ve-1 is a non-suppressor of wing disc phenotype of ft^k07918

(Garoia et al., 2000)

Other

Statement

Reference

pk³⁰, rho^ve-1, vn¹ has wing hair phenotype

(Hogan et al., 2011)

pk³⁰, rho^ve-1, vn¹ has wing vein phenotype

(Hogan et al., 2011)

rho^ve-1, vn¹ has wing vein phenotype

(Terriente-Félix and de Celis, 2009, Ralston and Blair, 2005, Martin-Blanco et al., 1999, de Celis, 1997, Milan et al., 1997)

Bant\lef^UAS.cGa, Scer\GAL4^Bx-MS1096, rho^ve-1 has wing vein phenotype

(Guichard et al., 2006)

Df(2R)ED3921, rho^ve-1 has wing vein L2 phenotype

(Ragab et al., 2006)

hry¹, rho^ve-1 has wing phenotype

(Biehs et al., 1998)

hry¹, rho^ve-1 has wing sensillum | ectopic phenotype

(Biehs et al., 1998)

rho⁹/rho^ve-1, vn¹ has wing vein phenotype

(Roch et al., 1998)

rho⁹/rho^ve-1, vn^M2 has wing vein phenotype

(Roch et al., 1998)

rho⁹/rho^ve-1, vn^M2/vn¹ has wing vein phenotype

(Roch et al., 1998)

rho^ve-1, vn¹ has crossvein phenotype

(Milan et al., 1997)

rho^ve-1, vn¹ has wing phenotype

(Wolfgang et al., 1996)

bs¹², rho^ve-1 has wing vein L4 phenotype

(Fristrom et al., 1994)

bs^A48, rho^ve-1 has wing vein L2 phenotype

(Fristrom et al., 1994)

bs^A48, rho^ve-1 has wing vein L5 phenotype

(Fristrom et al., 1994)

bs^A48, rho^ve-1 has wing vein L3 phenotype

(Fristrom et al., 1994)

bs^A48, rho^ve-1 has wing vein L4 phenotype

(Fristrom et al., 1994)

bs¹¹, rho^ve-1 has wing vein L2 phenotype

(Fristrom et al., 1994)

bs¹¹, rho^ve-1 has wing vein L5 phenotype

(Fristrom et al., 1994)

bs¹¹, rho^ve-1 has wing vein L3 phenotype

(Fristrom et al., 1994)

bs¹¹, rho^ve-1 has wing vein L4 phenotype

(Fristrom et al., 1994)

bs¹², rho^ve-1 has wing vein L2 phenotype

(Fristrom et al., 1994)

bs¹², rho^ve-1 has wing vein L5 phenotype

(Fristrom et al., 1994)

bs¹², rho^ve-1 has wing vein L3 phenotype

(Fristrom et al., 1994)

aos^hs.PSa, rho^ve-1 has wing vein L2 phenotype

(Sawamoto et al., 1994)

aos^hs.PSa, rho^ve-1 has wing vein L5 phenotype

(Sawamoto et al., 1994)

aos^hs.PSa, rho^ve-1 has wing vein L4 phenotype

(Sawamoto et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

rho^ve-1,vn¹ double mutants almost completely lack veins in the adult wing. This phenotype was not changed in rho^ve-1,vn¹,CycG^HR7 triple mutants.

The vein loss phenotype of rho^ve-1 is slightly enhanced in rho^ve-1,CycG^HR7 double mutants but the effect is limited to L4 vein.

(Nagel et al., 2016)

rho^ve-1, vn¹ double mutant wings retain wild-type hair polarity and ridge orientation.

Wings of homozygous pk³⁰, rho^ve-1 and vn¹ triple mutant flies lack veins L2-5. Wing anterior hairs of these mutants consistently have a posterior component to their polarity and posterior hairs have an anterior component to their polarity.

(Hogan et al., 2011)

One copy of rho^ve-1 enhances the reduction in wing blade area seen in homozygous sl² males.

One copy of rho^ve-1 significantly enhances the ectopic wing vein phenotype seen in sl² homozygotes.

One copy of rho^ve-1 partially suppresses the percentage of sl² mutant ommatidia that contain extra R7 photoreceptors. The number of R7 cells per ommatidium is also reduced.

(Murillo-Maldonado et al., 2011)

Introduction of one copy of kst¹ into a homozygous rho^ve-1 background completely suppresses the wing vein defect for L2-L4 and partially suppresses the defects in L5. A kst² heterozygous background results in a similar, but milder suppression.

A reduction in the level of AnnIX, through expression of AnnIX^{dsRNA.Scer\UAS} in the wing blade, under the control of Scer\GAL4^Bx-MS1096, restores wing vein formation in a rho^ve-1 background.

A Rab5² heterozygous background leads to full suppression of the L5 wing vein defect in rho^ve-1/Df(3L)ru-22 kst¹ mutants and 90% suppression in rho^ve-1/rho^ve-1 kst¹ flies.

A Rbsn-5^40-3 heterozygous background leads to just under 40% suppression of the L5 wing vein defect in both rho^ve-1/Df(3L)ru-22 kst¹ and rho^ve-1/rho^ve-1 kst¹ flies.

A Hrs^v28 heterozygous background leads to approximately 30% suppression of the L5 wing vein defect in both rho^ve-1/Df(3L)ru-22 kst¹ and rho^ve-1/rho^ve-1 kst¹ flies.

An Eps-15^e75 heterozygous background leads to approximately 70% suppression of the L5 wing vein defect in both rho^ve-1/Df(3L)ru-22 kst¹ and rho^ve-1/rho^ve-1 kst¹ flies.

A Vps28^B9 heterozygous background leads to approximately 90% suppression of the L5 wing vein defect in both rho^ve-1/Df(3L)ru-22 kst¹ and rho^ve-1/rho^ve-1 kst¹ flies.

A Vps25^A3 heterozygous background leads to approximately 90% suppression of the L5 wing vein defect in rho^ve-1/rho^ve-1 kst¹ flies.

A Vps20^I3 heterozygous background leads to approximately 90% suppression of the L5 wing vein defect in rho^ve-1/Df(3L)ru-22 kst¹ flies.

A shrb^G5 heterozygous background leads to almost full suppression of the L5 wing vein defect in rho^ve-1/Df(3L)ru-22 kst¹ mutants and 80% suppression in rho^ve-1/rho^ve-1 kst¹ flies.

(Tjota et al., 2011)

The loss of wing veins seen in rho^ve-1 homozygotes is not suppressed by Bap170^hfl1/+.

(Rendina et al., 2010)

Wing veins do not develop in rho^ve-1, vn¹ animals.

Overexpression of osa^Scer\UAS.cCa in the wing under the control of Scer\GAL4^salm-459.2 cannot induce vein formation in a rho^ve-1, vn¹ mutant background.

(Terriente-Félix and de Celis, 2009)

Expression of Ubqn^{dsRNA.Ex2.Scer\UAS} by Scer\GAL4^e22c in a heterozygous rho^ve-1 background leads to a normal anterior cross vein and partially restored posterior cross vein and L5 vein, while the distal portion of L4 and L3-4 M veins corresponding to the posterior portion of the wing remains weakened, compared with Ubqn^{dsRNA.Ex2.Scer\UAS}; Scer\GAL4^e22c single mutants.

(Li et al., 2007)

Df(2R)ED3921; rho^ve-1 flies show an enhancement of L5 vein loss compared to rho^ve-1 flies single mutants and partial loss of L2, a phenotype not seen in rho^ve-1 flies. There is no significant enhancement of L4 and L3 loss.

(Ragab et al., 2006)

The wings of rho^ve-1 vn¹ double mutants examined at 19, 21 or 24 hours after pupariation (AP) lack most longitudinal veins, with only the most proximal vein tissue intact 19 and 21 hours AP.

(Ralston and Blair, 2005)

rho^ve-1 double mutants, heterozygous for frc^RY34 exhibit the same phenotype as rho^ve-1 mutants.

(Yano et al., 2005)

rho^ve-1 vn¹ double homozygotes lack wing veins. This phenotype is partially suppressed by ash2^S112411 /ash2^S112411. The degree of suppression varies from development of L2 only to almost complete rescue, albeit with some abnormalities such as extra crossvein material or proximal fusions between L2 and L3 or L4 and L5. In 25% of cases, hollow, tube like wings are formed, probably due to detachment of dorsal and ventral layers.

(Angulo et al., 2004)

brm² enhances the loss of wing vein L5 seen in rho^ve-1 homozygotes. Snr1^E1/Snr1^R3 suppresses the loss of wing vein L5 seen in rho^ve-1 homozygotes and rho^ve-1 suppresses the Snr1^E1/Snr1^R3 extra wing vein phenotype. Snr1^E1 suppresses the shortened L5 wing vein that results from the interaction between rho^ve-1 and brm².

(Marenda et al., 2004)

The addition of bwk^Δ11 and vn¹ fails to enhance the extra wing vein phenotype seen in cic^D49/bwk^Δ11 animals.

(Roch et al., 2002)

When Egfr^f1/Egfr^t1 flies are raised at the non-permissive temperature (29^oC) in a rho^ve-1/rho^ve-1 background, there is an enhancement of the usual rho^ve-1 homozygous wing vein phenotype.

(Guichard et al., 1999)

vn¹ rho^ve-1 flies completely lack wing veins.

(Martin-Blanco et al., 1999)

h¹ rho^ve-1 / h¹ rho^ve-1 flies have ectopic bristles running between longitudinal veins.

(Biehs et al., 1998)

rho^ve-1/ast^K6 double heterozygotes do not have a visible phenotype. The phenotype of rho^ve-1 homozygotes is not dominantly altered by ast^K6.

(Kotarski et al., 1998)

rho⁹, vn^M2/rho^ve-1, vn¹ double mutants lack wing veins. bs⁰³²⁶⁷/bs²; rho⁹, vn^M2/rho^ve-1, vn¹ triple mutants show an almost wild type wing vein pattern.

(Roch et al., 1998)

rho^ve-1 vn¹ double mutant flies lack all the longitudinal veins and crossveins of the wing blade. Dorsal and ventral implants of rho^ve-1 vn¹ imaginal disc tissue into wild-type imaginal discs fail to differentiate veins.

(Milan et al., 1997)

vn¹ rho^ve-1 double homozygotes lack all longitudinal wing veins. Vein tissue differentiates in vn¹ rho^ve-1 double homozygotes when dpp^Scer\UAS.cSa is expressed in these flies using Scer\GAL4^C-580. rho^ve-1 suppresses the differentiation of thicker veins seen in tkv¹/tkv⁸ flies, and results in fewer veins in combination with either dpp^s4/dpp^s8 or tkv¹/tkv⁸.

(de Celis, 1997)

vn¹ rho^ve-1 flies lack wing veins.

(Wolfgang et al., 1996)

rho^ve-1 homozygotes which are also expressing argos^hs.PSa (using heat pulses from the second and third larval instar to pupal stage) lack most of wing veins L2-L4 and the entire L5 vein is eliminated. The campaniform sensilla on vein L3 usually remain intact.

(Sawamoto et al., 1994)

Xenogenetic Interactions

Statement

Reference

Moderate expression of Zzzz\lef^Scer\UAS.cGa under the control of Scer\GAL4^Bx-MS1096 in rho^ve-1 heterozygotes results in wing vein loss, while moderate Zzzz\lef^Scer\UAS.cGa expression (with Scer\GAL4^Bx-MS1096) alone doesn't have this phenotype.

(Guichard et al., 2006)

Loss of the distal tips of wing veins seen in rho^ve-1 mutant flies is suppressed by Pstu\aarA^Scer\UAS.cGa; Scer\GAL4^Bx-MS1096.

(Gallio et al., 2002)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (44)

Bloomington

628

rho^ve-1

603542

rho^ve-1 vn¹

2399

Df(3L)R-G5, rho^ve-1/TM6

1029

479

43636

106017

107310

Df(3L)R-G5, rho^ve-1/TM6

101596

Df(3L)R-G5, rho^ve-1 / TM6

106176

rho^ve-1 Coa¹/TM6

101936

bw¹ ; rho^ve-1 st¹

105933

mwh¹ rho^ve-1 hry¹

More stocks available...

Notes on Origin

Discoverer

Duncan, Jan. 1934.

(Lindsley and Zimm, 1992)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (12)

Reported As

Symbol Synonym

Rho^ve-1

(Zhu et al., 2017)

Rho^ve1

(Bidet et al., 2003)

rho-1^veinlet

(Gallio et al., 2002)

rho¹

(Yan et al., 2004)

rho^VE

(Wolfgang et al., 1996)

rho^ve-1

(Tsuboi et al., 2023, Duan et al., 2018, Kavaler et al., 2018, Valentine et al., 2014, Curtis et al., 2013, Hogan et al., 2011, Murillo-Maldonado et al., 2011, Pilgram et al., 2011, Li et al., 2007, Oishi et al., 2006)

rho^ve1

(Rougeot et al., 2013, Yano et al., 2005, Kotarski et al., 1998)

(Baonza and Garcia-Bellido, 1999)

ve¹

(Nagel et al., 2016, Johannes and Preiss, 2002, Garoia et al., 2000, Sotillos and Campuzano, 2000, Roch et al., 1998, Sapir et al., 1998, de Celis, 1997, Milan et al., 1997, Lindsley and Zimm, 1992, Wessendorf et al., 1992, Duncan, 1935)

Name Synonyms

rhomboidve

(Tjota et al., 2011)

veinlet

(Urban, 2006)

Secondary FlyBase IDs

References (69)

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