FlyBase Allele Report: Dmel\vtd[3]

General Information

Symbol

Dmel\vtd³

Species

D. melanogaster

Name

FlyBase ID

FBal0018066

Feature type

allele

Associated gene

Dmel\vtd

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Kennison and Tamkun, 1988)

Progenitor genotype

Caused by aberration

Df(3L)vtd³

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Schulze et al., 2001, Kennison and Tamkun, 1988)

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutation changes the level of w expression in ph-p^lac+3 flies; eye colour is lighter.

(Fauvarque et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

vtd³ is a suppressor of visible phenotype of Pc⁴

(Schulze et al., 2001)

vtd[+]/vtd³ is a suppressor of visible phenotype of hh^Mrt

(Schulze et al., 2001)

NOT Suppressor of

Statement

Reference

vtd³ is a non-suppressor of lethal phenotype of Ras85D^V12.sev, sev^S11.Tag:MYC

(Maixner et al., 1998)

Other

Statement

Reference

l(3)80Fj^2-30, vtd³ has partially lethal - majority die phenotype

(Schulze et al., 2001)

Phenotype Manifest In

Suppressor of

Statement

Reference

vtd³ is a suppressor of sex comb | ectopic phenotype of Pc⁴

(Schulze et al., 2001)

vtd[+]/vtd³ is a suppressor of wing vein phenotype of hh^Mrt

(Schulze et al., 2001)

vtd[+]/vtd³ is a suppressor of wing phenotype of hh^Mrt

(Schulze et al., 2001)

vtd³ is a suppressor of phenotype of Pc⁴

(Kennison and Tamkun, 1988)

Other

Statement

Reference

Kr^If-1, vtd[+]/vtd³ has eye phenotype

(Sollars et al., 2003)

Kr^If-1, vtd³ has eye phenotype

(Sollars et al., 2003)

l(3)80Fj^2-30, vtd³ has macrochaeta phenotype

(Schulze et al., 2001)

l(3)80Fj^2-30, vtd³ has eye phenotype

(Schulze et al., 2001)

l(3)80Fj^2-30, vtd³ has sex comb phenotype

(Schulze et al., 2001)

l(3)80Fj^2-30, vtd³ has abdominal segment 5 & cuticle phenotype

(Schulze et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

55+/-8% of Kr^If-1/+ flies born to vtd³/+ mothers have outgrowths with ectopic vibrissae protruding from the ventral region of the eye, compared to less than 0.1% of Kr^If-1/+ flies born to isogenised wild-type mothers.

(Sollars et al., 2003)

Escapers of the lethality with l(3)80Fj^2-30 alleles show rough and notched eyes, small thin bristles and male escapers show reduced sex combs and unpigmented patches in the fifth abdominal segment.

(Schulze et al., 2001)

The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is not suppressed by vtd³.

(Maixner et al., 1998)

Suppresses the extra sex comb phenotype of Pc⁴, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc⁴/+ extra sex combs phenotype.

(Kennison and Tamkun, 1988)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

vtd³

(Vázquez et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

Open Close