Allele Dmel\w¹

General Information
Symbol	Dmel\w¹	Species	D. melanogaster
Name		FlyBase ID	FBal0018074
Feature type	allele	Associated gene	Dmel\w
Also Known As	w

Map ( GBrowse )	Untitled Document
Allele class	loss of function allele, amorphic allele - genetic evidence, hypomorphic allele - genetic evidence
Mutagen	spontaneous
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	amorphic allele - genetic evidence (Judd, 1995) hypomorphic allele - genetic evidence (Lloyd et al., 2002) loss of function allele (Sabl and Birchler, 1993)
Mutagen	spontaneous (Zachar and Bingham, 1982, Driver et al., 1989)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:2,690,518..2,690,530 (Sabl and Birchler, 1993, Dalby and O'Hare, 1991, O'Hare, 1991, O'Hare et al., 1991, Judd, 1995, Driver et al., 1989)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of a Doc element. (Judd, 1995) Insertion of a 5.7kb Doc element. (Sabl and Birchler, 1993) Insertion of Doc element at +3700bp. (Dalby and O'Hare, 1991) Insertion of Doc element into the proximal region of w. (O'Hare, 1991) Doc element inserted into w promoter region. (O'Hare et al., 1991) Insertion of 4.9kb Doc element, close to the site of transcription initiation. 13bp of w sequence from +3700 to +3688 is duplicated, and is present at both ends of the Doc insertion (nucleotide positions as in FBrf0041384). The Doc element is inserted in the same orientation as the direction of w transcription. (Driver et al., 1989) 5kb Doc insert at +3.71; Origin = insertion of w^a copia; '-' values to left (telomere) end; '+' values to right (centromere) end.
Caused by insertion	Doc{}w¹ (Sabl and Birchler, 1993, Dalby and O'Hare, 1991, O'Hare, 1991, O'Hare et al., 1991, Judd, 1995, Driver et al., 1989)
Carried on aberration	Binsinscy (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) Bwinscy (FlyBase Curators, 2006-, Sekelsky et al., 1999) FM0 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM4-w¹B⁺ (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28) FM4-wfB (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28) FM6-vAa (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM6-w¹ (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28) FM7h (FlyBase Curators, 2006-) FM7h-N^Placr (FlyBase Curators, 2006-, Heitzler, 1997) FM7i (FlyBase Curators, 2006-, Heitzler, 1997) FM7j (FlyBase Curators, 2006-, Heitzler, 1997) FM7j-B¹ (FlyBase Curators, 2006-, Roote, 2001.12.11) FM7w (FlyBase Curators, 2006-, Sekelsky et al., 1999) winscy (FlyBase Curators, 2006-, Lindsley and Zimm, 1992)
Cytology
Phenotypic Data
Phenotypic Class
	courtship behavior defective \| chemical conditional (Lee et al., 2008) eye color defective (Smolik-Utlaut and Gelbart, 1987, Gehring et al., 1984, Lloyd et al., 2002, Plough and Ives, 1934) eye color defective, with w^{enh.Fab-7.1.2.m1-2} (Schweinsberg et al., 2004) eye color defective, with w^{enh.Fab-7.1.2.m1-5} (Schweinsberg et al., 2004) eye color defective, with w^{enh.Fab-7.1.2.m3-4} (Schweinsberg et al., 2004) eye color defective, with w^{enh.Fab-7.1.2} (Schweinsberg et al., 2004) eye color defective \| recessive (Pastink et al., 1987, Kaufman, 1969) visible \| recessive (Gehring et al., 1984, )
Phenotype Manifest In
	Malpighian tubule (Gehring et al., 1984, ) ocellus pigment granule (Gehring et al., 1984, ) pigment cell (Smolik-Utlaut and Gelbart, 1987, Gehring et al., 1984, Pastink et al., 1987, Lloyd et al., 2002, Plough and Ives, 1934, Zachar and Bingham, 1982, Kaufman, 1969) pigment cell, with w^{enh.Fab-7.1.2.m1-2} (Schweinsberg et al., 2004) pigment cell, with w^{enh.Fab-7.1.2.m1-5} (Schweinsberg et al., 2004) pigment cell, with w^{enh.Fab-7.1.2.m3-4} (Schweinsberg et al., 2004) pigment cell, with w^{enh.Fab-7.1.2} (Schweinsberg et al., 2004) testis pigment cell (Gehring et al., 1984, )
Detailed Description
	Statement Reference Mutant males display negligible intermale courtship upon recurring ethanol administration with 70% ethanol, in contrast to wild-type males which show intermale courtship after repeated ethanol exposure. (Lee et al., 2008) Homozygotes have white eyes with only <1% red pigment (compared to 100% pigment in wild type). (Lloyd et al., 2002) Bleach white eyes. (O'Hare et al., 1991) Eye colour: w^sp1/w¹ flies have brown eyes at eclosion, which become somewhat darker with age. (Pastink et al., 1987) White eye colour, suppresses z¹. (Smolik-Utlaut and Gelbart, 1987) Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless. (Gehring et al., 1984) Eye colour: bleach white. (Zachar and Bingham, 1982) Eye colour: The w^cf2 eye colour is not diluted when w^cf2 is in transheterozygous combination with w¹. (Kaufman, 1969) Eye colour: w^dil/w¹ flies have darker eyes than g¹ and lighter eyes than pn¹. (Plough and Ives, 1934) Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless. Eye colour: brown at eclosion, darker after 4-5 days, as w¹/w^sp1.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference w¹/w^e(g) is an enhancer of eye color defective phenotype of g² (Lloyd et al., 2002) w¹/w^e(g) is an enhancer of eye color defective phenotype of g^50e (Lloyd et al., 2002) w¹/w^e(g) is an enhancer of eye color defective phenotype of g^53d (Lloyd et al., 2002)
Other
Statement Reference su(f)⁴/su(f)¹, w¹ has eye color defective phenotype (Schalet, 1972)
Phenotype Manifest In
NOT suppressed by
Statement Reference w¹ has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968)
Enhancer of
Statement Reference w¹/w^e(g) is an enhancer of pigment cell phenotype of g² (Lloyd et al., 2002) w¹/w^e(g) is an enhancer of pigment cell phenotype of g^50e (Lloyd et al., 2002) w¹/w^e(g) is an enhancer of pigment cell phenotype of g^53d (Lloyd et al., 2002)
Suppressor of
Statement Reference w¹ is a suppressor of phenotype of z¹ (Judd, 1995)
Other
Statement Reference su(f)⁴/su(f)¹, w¹ has pigment cell phenotype (Schalet, 1972)
Additional Comments
Genetic Interactions
Statement Reference Flies with a w¹/w^e(g) mutant genotype enhance the eye colour defective phenotype of g², g^50e and g^53d homozygous mutants leading to a greater reduction of red pigment in the eye. (Lloyd et al., 2002) A suppressor of the repression on w by z¹. (Judd, 1995) w¹ su(f)⁴/w^a su(f)¹ females have a w¹ phenotype at 24-25^oC. w^a su(f)⁴/Y males have an eye colour intermediate between that of w¹ and w^a at 17-18^oC. (Schalet, 1972)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Complements	w^sp1
Partially complements	w^sp1 (Green, 1959)
Rescued by	w¹ is rescued by w^+t12 (Gehring et al., 1984)
Partially rescued by	w¹ is partially rescued by w^+mC (Lloyd et al., 2002) w¹ is partially rescued by w^+tAR (Lloyd et al., 2002) w¹ is partially rescued by w^HSBJ (Lloyd et al., 2002)
Comments
Stocks ( 661 )
Bloomington	145 w¹ 2390 w¹ 1495 y¹ w¹ 3132 w¹; vg¹ 5298 w¹ dsh¹
Kyoto	101196 w¹ 105757 w¹ 107303 w¹ 109555 Binscy, w¹ 106349 y¹ w¹ 101198 w¹ ct¹ 101202 w¹ sn³
	More stocks available...
Notes on Origin
Discoverer	Morgan, March 1910.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	w (Schalet, 1972, Plough and Ives, 1934, Pastink et al., 1987) w1 (Soriano et al., 1997) w¹ (Lee et al., 2008, Singh et al., 2009)
Name Synonym
Secondary FlyBase IDs

References ( 61 )

Generate a list of	All references relating to this allele ( 61 )

List References by type	Research paper ( 52 ) Personal communication to FlyBase ( 3 ) Abstract ( 2 ) FlyBase analysis ( 1 ) Book ( 2 ) Stock list ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...

Allele Dmel\w1

Allele Dmel\w¹