A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Dmel\w1

General Information
SymbolDmel\w1SpeciesD. melanogaster
NameFlyBase IDFBal0018074
Feature typealleleCreated / Updated2006-05-15/2006-05-15
Associated geneDmel\w
Allele classamorph, loss of function, hypomorph
Mutagenspontaneous
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Allele class
Mutagen
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      5kb Doc insert at +3.71; Origin = insertion of wa copia; '-' values to left (telomere) end; '+' values to right (centromere) end.
       
      Insertion of 4.9kb Doc element, close to the site of transcription initiation. 13bp of w sequence from +3700 to +3688 is duplicated, and is present at both ends of the Doc insertion (nucleotide positions as in FBrf0041384). The Doc element is inserted in the same orientation as the direction of w transcription.
      Insertion of Doc element into the proximal region of w.
      Insertion of Doc element at +3700bp.
      Doc element inserted into w promoter region.
      Insertion of a 5.7kb Doc element.
      Insertion of a Doc element.
      Assay mode
      Caused by insertion
      Carried on aberration
      Cytology
      hide Phenotypic Data
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      hide Phenotype Manifest In
      hide Detailed Description
      Statement
      Reference
      Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless. Eye colour: brown at eclosion, darker after 4-5 days, as w1/wsp1.
       
      Eye colour: bleach white.
      Eye colour: white. Ocellus colour: colourless. Testis colour: colourless. Malpighian tubule colour: colourless.
      White eye colour, suppresses z1.
      Eye colour: wsp1/w1 flies have brown eyes at eclosion, which become somewhat darker with age.
      Bleach white eyes.
      Eye colour: The wcf2 eye colour is not diluted when wcf2 is in transheterozygous combination with w1.
      Eye colour: wdil/w1 flies have darker eyes than g1 and lighter eyes than pn1.
      Homozygotes have white eyes with only <1% red pigment (compared to 100% pigment in wild type).
      hide Interactions
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      hideEnhancer of
      Statement
      Reference
      w1/we(g) is an enhancer of eye color defective phenotype of g53d
      w1/we(g) is an enhancer of eye color defective phenotype of g2
      w1/we(g) is an enhancer of eye color defective phenotype of g50e
      hideOther
      Statement
      Reference
      hide Phenotype Manifest In
      hideNOT suppressed by
      Statement
      Reference
      w1 has phenotype, non-suppressible by su(Hw)2
      hideEnhancer of
      Statement
      Reference
      w1/we(g) is an enhancer of pigment cell phenotype of g53d
      w1/we(g) is an enhancer of pigment cell phenotype of g2
      w1/we(g) is an enhancer of pigment cell phenotype of g50e
      hideSuppressor of
      Statement
      Reference
      w1 is a suppressor of phenotype of z1
      hideOther
      Statement
      Reference
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      w1 su(f)4/wa su(f)1 females have a w1 phenotype at 24-25oC. wa su(f)4/Y males have an eye colour intermediate between that of w1 and wa at 17-18oC.
      A suppressor of the repression on w by z1.
      Flies with a w1/we(g) mutant genotype enhance the eye colour defective phenotype of g2, g50e and g53d homozygous mutants leading to a greater reduction of red pigment in the eye.
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      Statement
      Reference
      hide Complementation & Rescue Data
      Complements
       
      Partially complements
      Rescued by
      Partially rescued by
      w1 is partially rescued by w+tAR
      w1 is partially rescued by w+mC
      w1 is partially rescued by wHSBJ
      Comments
      hide Stocks ( 1720 )
      Bloomington
      145
      2390
      1495
      Kyoto
      101196
      105757
      107303
      106349
      101198
      101202
      hide Notes on Origin
      Discoverer
      Morgan, March 1910.
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      w1
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 59 )
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        All research papers listed in FlyBase were published before 2006