FB2020_06, released Dec 22, 2020

Allele: Dmel\w118

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General Information
Symbol
Dmel\w118
Species
D. melanogaster
Name
FlyBase ID
FBal0018157
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl nitrosourea
(Pastink et al., 1988)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Cytology
      Nature of the lesion
      Statement
      Reference

      There is no detectable alteration in the restriction enzyme profile compared to wild-type.

      (Pastink et al., 1988)
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      w118 mutant larvae are less responsive to gentle touch.

      (Titlow et al., 2014)

      w118 flies exhibit increased survival time compared to wild-type.

      (Oxenkrug, 2010)

      Eye colour: white.

      (Lee and Carthew, 2003, Pastink et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      w118 is a suppressor of touch response defective phenotype of SmnE33

      (Titlow et al., 2014)
      NOT Suppressor of
      Statement
      Reference

      w118 is a non-suppressor of locomotor behavior defective phenotype of SmnE33

      (Titlow et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The mechanosensory phenotype seen in SmnE33 larvae is rescued by crossing with w118, but crawling speed is not restored to wild-type or SmnE33/+ levels.

      (Titlow et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (26)
      Notes on Origin
      Discoverer

      Pastink.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      w118
      (Titlow et al., 2014, Kyrchanova et al., 2011, Oxenkrug, 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)