• Home
• Tools
  • BLAST
  • GBrowse
  • QueryBuilder
  • TermLink
  • ImageBrowse
  • Interactions Browser
  • Apollo
  • CytoSearch
  • QuickSearch
  • Batch Download
  • Coordinate Converter
  • Google™ FlyBase
  • Find A Person
  • Update An Address
  • Add A New Person
• Files
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases FTP
  • Genomes FTP
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Synteny Table
  • Drosophilidae
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All resources
  • Interactive Fly
  • Textpresso for Fly
  • AAA site
  • BDGP
  • DHGP
  • DGRC
  • Model Organisms
  • Stock Collections:
  • Bloomington
  • DrosDel
  • Ehime
  • Exelixis (Harvard)
  • GDP (Baylor)
  • Kyoto
  • NIG-Fly
  • Szeged
  • Tucson
  • VDRC
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Known Problems
  • Contact FlyBase
• Archives
  • Prior Home Page
  • R4.3 BLAST
  • R4.3 GBrowse
  • Older Archives

Allele Dmel\w¹¹¹⁸

General Information
Symbol	Dmel\w1118	Species	D. melanogaster
Name		FlyBase ID	FBal0018186
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\w
Allele class	loss of function
Mutagen	spontaneous
Nature of the Allele
Allele class	loss of function (Kurkulos et al., 1991, Campbell and Nash, 2001, Lloyd et al., 2002)
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype	wDZL
Nature of the lesion	Statement Reference deletion of part of gene   The 5' half of w is deleted. (Rabinow and Birchler, 1989) Partial deletion of w sequence, deletion is 5' to site of insertion of P-element in whd80k17. (Engels et al., 1990) Partial deletion of w. (Dalby and O'Hare, 1991) Deletion of sequences including exon 1. (Kurkulos et al., 1991)
Assay mode
Cytology
Phenotypic Data
Phenotypic Class
	visible (Ahmad and Golic, 1996) visible | recessive   eye color defective (Lloyd et al., 2002, ) eye color defective (with wT40) (Bloyer et al., 2003) eye color defective (with wph-p.lac+3) (Bloyer et al., 2003, Perrin et al., 2003) eye color defective, with wmC.ph-p.813bis (Bloyer et al., 2003) eye color defective, with wmC.ph-p.813 (Bloyer et al., 2003) eye color defective, with wmC.ph-p.812 (Bloyer et al., 2003) eye color defective, with wmC.ph-p.418bis (Bloyer et al., 2003) eye color defective, with wmC.ph-p.418 (Bloyer et al., 2003) eye color defective, with wmC.ph-d.826 (Bloyer et al., 2003) eye color defective, with wprod.PRE (Ringrose et al., 2003) eye color defective, with weya.PRE (Ringrose et al., 2003) eye color defective, with wcad.PRE (Ringrose et al., 2003) eye color defective, with waPKC.PRE (Ringrose et al., 2003) locomotor behavior defective (Liu et al., 2007) chemical resistant | male (Campbell and Nash, 2001)
Phenotype Manifest In
	pigment cell, with weya.PRE (Ringrose et al., 2003) pigment cell, with wcad.PRE (Ringrose et al., 2003) pigment cell, with wprod.PRE (Ringrose et al., 2003) pigment cell, with waPKC.PRE (Ringrose et al., 2003) pigment cell (with wph-p.lac+3) (Perrin et al., 2003) pigment cell (Ahmad and Golic, 1996, Lloyd et al., 2002, )
Detailed Description
	Statement Reference Eye colour: white.   Not susceptible to p-Cresol. (O'Dell, 1993) Eye colour: wph-p.lac+3/w1118 females have an orange eye colour. (Perrin et al., 2003) Male w1118 flies have an increased resistance to the anesthetic enflurane compared to wild-type controls, as judged by climbing ability. This effect is true whether enflurane resistance is measured in regular light or red light. Male w1118 flies have an increased resistance to the anesthetic halothane compared to wild-type controls when climbing ability is measured in regular light. However, this resistance varies from only modest to marginal when climbing ability is measured in red light. (Campbell and Nash, 2001) Homozygotes have white eyes with only <1% red pigment (compared to 100% pigment in wild type). (Lloyd et al., 2002) Mutants show a reduced decay of the initial locomotor activity in an open field arena compared to wild-type flies. (Liu et al., 2007)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference w1118, wmC.ph-p.812 has eye color defective phenotype, enhanceable by Df(3L)th102 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, enhanceable by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, enhanceable by Df(3L)th102 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by Df(3L)th102 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, enhanceable by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by Df(3L)th102 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, enhanceable by Pc16 (Bloyer et al., 2003) wT40/w1118 has eye color defective phenotype, enhanceable by Psc[+]/PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by Df(3L)th102 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by Df(3R)red3l (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by In(3R)Ubx7LLatsR (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by PscArp1 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by kis2 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by mor1 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, enhanceable by trxunspecified (Bloyer et al., 2003)
NOT Enhanced by
Statement Reference w1118, wmC.ph-p.812 has eye color defective phenotype, non-enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, non-enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, non-enhanceable by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-enhanceable by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-enhanceable by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-enhanceable by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, non-enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, non-enhanceable by trxunspecified (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, non-enhanceable by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, non-enhanceable by trxunspecified (Bloyer et al., 2003)
Suppressed by
Statement Reference w1118, wcad.PRE has eye color defective phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) w1118, weya.PRE has eye color defective phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.813bis has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) w1118, waPKC.PRE has eye color defective phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, wprod.PRE has eye color defective phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.813 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, suppressible by Alh1/Alh[+] (Perrin et al., 2003) wT40/w1118 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) wT40/w1118 has eye color defective phenotype, suppressible | partially by Psc[+]/Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, suppressible | partially by E(Pc)unspecified (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, suppressible | partially by Psc1 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, suppressible | partially by Sce1 (Bloyer et al., 2003) wph-p.lac+3/w1118 has eye color defective phenotype, suppressible | partially by ph-p410 (Bloyer et al., 2003)
NOT suppressed by
Statement Reference w1118, wmC.ph-p.812 has eye color defective phenotype, non-suppressible by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, non-suppressible by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, non-suppressible by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-p.812 has eye color defective phenotype, non-suppressible by In(3R)Ubx7LLatsR (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-suppressible by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-suppressible by Pc16 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-suppressible by Sce1 (Bloyer et al., 2003) w1118, wmC.ph-d.826 has eye color defective phenotype, non-suppressible by trxE2 (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, non-suppressible by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.418bis has eye color defective phenotype, non-suppressible by trxunspecified (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, non-suppressible by Df(3R)red3l (Bloyer et al., 2003) w1118, wmC.ph-p.418 has eye color defective phenotype, non-suppressible by trxunspecified (Bloyer et al., 2003)
Enhancer of
Statement Reference w1118 is an enhancer | conditional qualifier of chemical sensitive phenotype of mud4 (Campbell and Nash, 2001) we(g)/w1118 is an enhancer of eye color defective phenotype of g53d (Lloyd et al., 2002) w1118 is an enhancer | conditional qualifier of chemical sensitive phenotype of nahar38 (Campbell and Nash, 2001) we(g)/w1118 is an enhancer of eye color defective phenotype of g2 (Lloyd et al., 2002) we(g)/w1118 is an enhancer of eye color defective phenotype of g50e (Lloyd et al., 2002)
Suppressor of
Statement Reference w1118 is a suppressor of courtship defective | male phenotype of g50e (Lloyd et al., 2002)
Phenotype Manifest In
Suppressed by
Statement Reference w1118, wcad.PRE has pigment cell phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, weya.PRE has pigment cell phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, waPKC.PRE has pigment cell phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) w1118, wprod.PRE has pigment cell phenotype, suppressible by ph-p[+]/ph-p410 (Ringrose et al., 2003) wph-p.lac+3/w1118 has pigment cell phenotype, suppressible by Alh1/Alh[+] (Perrin et al., 2003)
Enhancer of
Statement Reference we(g)/w1118 is an enhancer of pigment cell phenotype of g53d (Lloyd et al., 2002) we(g)/w1118 is an enhancer of pigment cell phenotype of g2 (Lloyd et al., 2002) we(g)/w1118 is an enhancer of pigment cell phenotype of g50e (Lloyd et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference Flies carrying one copy of either wcad.PRE, wprod.PRE, weya.PRE or waPKC.PRE in a w1118/w1118; ph-p410/+ double mutant background have darker eyes than flies with one copy of wcad.PRE, wprod.PRE, weya.PRE or waPKC.PRE in a single mutant w1118/w1118 background. (Ringrose et al., 2003) Eye colour: wph-p.lac+3/w1118 ; Alh1/+ females have a red eye colour. (Perrin et al., 2003) nahar38, w1118 mutant flies show the same sensitivity to 0.1% enflurane or halothane when tested under red light as nahar38 mutant flies do. However, nahar38, w1118 mutant flies show a much higher sensitivity to 0.05% enflurane or halothane when tested under ambient light than nahar38 mutant flies do. (Campbell and Nash, 2001) Flies with a w1118/we(g) mutant genotype enhance the eye colour defective phenotype of g2, g50e and g53d homozygous mutants leading to a greater reduction of red pigment in the eye. w1118, g50e double mutant flies do not show the increased male-male courtship behaviour that single g50e mutants exhibit. (Lloyd et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 28812 )
Bloomington	3605 w1118 5905 w1118 6326 w1118 7217 w1118; P{Jbz}1 4631 w1118; P{418}T3 6759 P{GMRGS}1, w1118 10074 P{EP}EP773 w1118 10080 P{EP}EP335 w1118 10081 P{EP}EP427 w1118
Kyoto	107122 w1118 108479 w1118 108736 w1118
	More stocks available...
Notes on Origin
Discoverer	R. Levis.
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	w1118 (Liu et al., 2007)
Name Synonym
Secondary FlyBase IDs
References ( 27 )
Generate a list of	All references relating to this allele ( 27 )
List References by type	Research paper  ( 25 ) Review  ( 2 )
Recent research papers ( 1 )
	Liu et al., 2007, Genetics 175(3): 1197--1212 Exploratory activity in Drosophila requires the kurtz nonvisual arrestin. [FBrf0200160] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2006 Show reviews ...