Allele Dmel\w^a2

General Information
Symbol	Dmel\w^a2	Species	D. melanogaster
Name	apricot-2	FlyBase ID	FBal0018196
Feature type	allele	Associated gene	Dmel\w

Allele class
Mutagen	spontaneous
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	spontaneous (Zachar and Bingham, 1982)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Point mutation in the structural portion of w. (Rabinow et al., 1991) Point mutation. (Rabinow and Birchler, 1989, Birchler and Hiebert, 1989, Csink et al., 1994, Soriano et al., 1995, Bhadra and Birchler, 1996, Larsson et al., 1996, Bhadra et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class
	eye color defective (Bhadra et al., 1997, Peng and Mount, 1995, Xie and Birchler, 2012) eye color defective \| recessive (Frolov et al., 1998) visible \| recessive
Phenotype Manifest In
	eye (Xie and Birchler, 2012) Malpighian tubule pigment cell (Zachar and Bingham, 1982, Frolov et al., 1998, Peng and Mount, 1995)
Detailed Description
	Statement Reference Fails to respond to E(w^a). (Birchler and Hiebert, 1989) Eye colour: orange-brown. (Zachar and Bingham, 1982) Eye colour: orange; darker in male. Malpighian tubule colour: colourless.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference w^a2 has eye color defective phenotype, enhanceable by Dp(2;2)Pdup-3/+ (Xie and Birchler, 2012)
Suppressed by
Statement Reference w^a2 has eye color defective \| recessive phenotype, suppressible by Low¹ (Bhadra et al., 1997) w^a2 has eye color defective phenotype, suppressible \| partially by Df(2R)Pdel-1/+ (Xie and Birchler, 2012) w^a2 has eye color defective phenotype, suppressible \| partially by Inr-a^EMS2/Inr-a[+] (Xie and Birchler, 2012)
Phenotype Manifest In
Enhanced by
Statement Reference w^a2 has eye phenotype, enhanceable by Dp(2;2)Pdup-3/+ (Xie and Birchler, 2012)
NOT Enhanced by
Statement Reference w^a2 has phenotype, non-enhanceable by B52^ED (Peng and Mount, 1995) w^a2 has phenotype, non-enhanceable by Doa³ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁴ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁵ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁶ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁷ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁸ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa⁹ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Doa^HD (Rabinow and Birchler, 1989) w^a2 has phenotype, non-enhanceable by Rm62^D (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Rm62^Dem (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Rm62^E (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Rm62^F (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Rm62^H (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Rm62^K (Csink et al., 1994) w^a2 has phenotype, non-enhanceable by Ufo¹ (Bhadra et al., 1997)
Suppressed by
Statement Reference w^a2 has eye phenotype, suppressible \| partially by Df(2R)Pdel-1/+ (Xie and Birchler, 2012) w^a2 has eye phenotype, suppressible \| partially by Inr-a^EMS2/Inr-a[+] (Xie and Birchler, 2012) w^a2 has phenotype, suppressible by Inr-a^EMS3 (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^EMS4 (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^EMS5 (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^hd1 (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^γb (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^γc (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Inr-a^γd (Rabinow et al., 1991) w^a2 has phenotype, suppressible by Mow^gamma (Bhadra and Birchler, 1996) w^a2 has phenotype, suppressible by Wow^ems1 (Birchler et al., 1994) w^a2 has phenotype, suppressible by Wow^hd1 (Birchler et al., 1994) w^a2 has phenotype, suppressible by Wow^γb (Birchler et al., 1994) w^a2 has phenotype, suppressible by Wow^γe (Birchler et al., 1994) w^a2 has pigment cell phenotype, suppressible by Low¹ (Bhadra et al., 1997) w^a2 has pigment cell phenotype, suppressible by RpLP0⁰¹⁵⁴⁴ (Frolov and Birchler, 1998)
NOT suppressed by
Statement Reference w^a2 has phenotype, non-suppressible by Doa³ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁴ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁵ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁶ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁷ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁸ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa⁹ (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by Doa^HD (Rabinow and Birchler, 1989) w^a2 has phenotype, non-suppressible by east¹ (Chapman and Bingham, 1985) w^a2 has phenotype, non-suppressible by Rm62^D (Csink et al., 1994) w^a2 has phenotype, non-suppressible by Rm62^Dem (Csink et al., 1994) w^a2 has phenotype, non-suppressible by Rm62^E (Csink et al., 1994) w^a2 has phenotype, non-suppressible by Rm62^F (Csink et al., 1994) w^a2 has phenotype, non-suppressible by Rm62^H (Csink et al., 1994) w^a2 has phenotype, non-suppressible by Rm62^K (Csink et al., 1994) w^a2 has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968) w^a2 has phenotype, non-suppressible by Ufo¹ (Bhadra et al., 1997)
Additional Comments
Genetic Interactions
Statement Reference The addition of Inr-a[EMS2]/+ or Df(2R)Pdel-1/+ darkens the eye colour of w[a2] flies. The addition of Dp(2;2)Pdup-3/+ lightens the eye colour of w[a2] flies. (Xie and Birchler, 2012)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	150 w^a2
Kyoto	101215 w^a2
Notes on Origin
Discoverer	Bridges, 1929.

Comments
	The alkylating agent ENU at high concentration, but not MMS or EMS, induces a significant increase in the frequency of somatic revertant sectors in the eye in w^a2 flies. (Soriano et al., 1995) Shows no interaction with "Msu" mutations. (Csink et al., 1994) mle⁴ has no effect on the dosage compensation of w^e, w^apl, w^F4-2, w^a2, Dp(1;1)w⁺61e19 or wⁱ. (Hiebert and Birchler, 1994)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	w^a2 (Xie and Birchler, 2012) wa2 (Soriano et al., 1997)
Name Synonym	apricot-2
Secondary FlyBase IDs

References ( 25 )

Generate a list of	All references relating to this allele ( 25 )

List References by type	Research paper ( 23 ) Abstract ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Xie and Birchler, 2012, G3 (Bethesda) 2(6): 701--706 Identification of Inverse Regulator-a (Inr-a) as Synonymous with Pre-mRNA Cleavage Complex II Protein (Pcf11) in Drosophila. [FBrf0218562] Show all research papers ...

Allele Dmel\wa2

Allele Dmel\w^a2