Allele Dmel\w^aM

General Information
Symbol	Dmel\w^aM	Species	D. melanogaster
Name	apricot of Mossige	FlyBase ID	FBal0018205
Feature type	allele	Associated gene	Dmel\w
Also Known As	w^aRM

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	spontaneous (Mount et al., 1988)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:2,686,840..2,686,844 (Csink et al., 1994, Bhadra and Birchler, 1996, Bhadra et al., 1997, Bhadra et al., 1997, Rabinow and Birchler, 1989)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	w^a (Carbonare and Gehring, 1985, Mount et al., 1988, Rabinow and Birchler, 1989, Birchler and Hiebert, 1989, Peng and Mount, 1990, Rabinow et al., 1991, Rabinow et al., 1993, Bhadra and Birchler, 1996, Bhadra et al., 1997)
Nature of the lesion	Statement Reference Insertion of a transposable element into the 5' LTR of the copia element present in w^a. (Bhadra et al., 1997) Transposable element insertion into copia 5' LTR. (Bhadra and Birchler, 1996) Transposable element insertion into copia 5' LTR. (Csink et al., 1994) Insertion of 2.3kb into or near the 5' LTR of the w^a copia insert. (Rabinow et al., 1993) Insertion of 2.3kb in the 5'-LTR of copia. (Hiebert and Birchler, 1992) Transposable element insertion in copia 5' LTR. (Birchler and Hiebert, 1989, Rabinow et al., 1991) Insertion in the copia 5' LTR of w^a. (Rabinow and Birchler, 1989) Insertion of 2.3 kb into the copia element of w^a. (Mount et al., 1988) Insertion of additional sequences into the w locus. (Carbonare and Gehring, 1985) 2.3kb insertion in copia 5' LTR of w^a.
Caused by insertion	?{}w^aM (Rabinow and Birchler, 1989, Bhadra et al., 1997, Csink et al., 1994, Bhadra and Birchler, 1996) copia{}w^a (Csink et al., 1994, Bhadra and Birchler, 1996, Bhadra et al., 1997, Bhadra et al., 1997, Rabinow and Birchler, 1989)
Cytology
Phenotypic Data
Phenotypic Class
	eye color defective (Bhadra et al., 1997, ) visible \| recessive
Phenotype Manifest In
	pigment cell (Carbonare and Gehring, 1985, )
Detailed Description
	Statement Reference Eye pigmentation is restored to 80% of wild type levels. (Carbonare and Gehring, 1985) Intermediate between w^a and wild-type in phenotype. (Green, 1959) Eye colour: darker than w^a, with more brown pigment. Eye colour: mottled, with mw¹.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference w^aM has phenotype, enhanceable by E(w^a)¹ (Birchler and Hiebert, 1989, Mount et al., 1988) w^aM has phenotype, enhanceable by Mow^gamma (Bhadra and Birchler, 1996) w^aM has phenotype, enhanceable by mw^3P (Birchler et al., 1989) w^aM has phenotype, enhanceable by Rm62^D (Csink et al., 1994) w^aM has phenotype, enhanceable by Rm62^Dem (Csink et al., 1994) w^aM has phenotype, enhanceable by Rm62^E (Csink et al., 1994) w^aM has phenotype, enhanceable by Rm62^F (Csink et al., 1994) w^aM has phenotype, enhanceable by Rm62^H (Csink et al., 1994) w^aM has phenotype, enhanceable by Rm62^K (Csink et al., 1994) w^aM has phenotype, enhanceable by su(f)¹ (Mount et al., 1988) w^aM has phenotype, enhanceable by Wow^ems1 (Birchler et al., 1994) w^aM has phenotype, enhanceable by Wow^hd1 (Birchler et al., 1994) w^aM has phenotype, enhanceable by Wow^γb (Birchler et al., 1994) w^aM has phenotype, enhanceable by Wow^γe (Birchler et al., 1994) w^aM has pigment cell phenotype, enhanceable by In(3)Msu¹/+ (Csink et al., 1994) w^aM has pigment cell phenotype, enhanceable by In(3)Msu²/+ (Csink et al., 1994)
NOT Enhanced by
Statement Reference w^aM has phenotype, non-enhanceable by Low¹ (Bhadra et al., 1997) w^aM has phenotype, non-enhanceable by mw^2a (Birchler et al., 1989) w^aM has phenotype, non-enhanceable by Ufo¹ (Bhadra et al., 1997)
Suppressed by
Statement Reference w^aM has phenotype, suppressible by Doa³ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁴ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁵ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁶ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁷ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁸ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa⁹ (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Doa^HD (Rabinow and Birchler, 1989) w^aM has phenotype, suppressible by Inr-a^EMS3 (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^EMS4 (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^EMS5 (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^hd1 (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^γb (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^γc (Rabinow et al., 1991) w^aM has phenotype, suppressible by Inr-a^γd (Rabinow et al., 1991) w^aM has phenotype, suppressible by su(w^a)¹⁵ (Mount et al., 1988) w^aM has phenotype, suppressible by su(w^a)¹⁶ (Mount et al., 1988) w^aM has phenotype, suppressible by su(w^a)¹⁷ (Mount et al., 1988) w^aM has phenotype, suppressible by su(w^a)^unspecified
NOT suppressed by
Statement Reference w^aM has phenotype, non-suppressible by Low¹ (Bhadra et al., 1997) w^aM has phenotype, non-suppressible by Ufo¹ (Bhadra et al., 1997)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Kyoto	101220 w^aM
Notes on Origin
Discoverer	Mossige.
	Arose on: Basc. (Green, 1959)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	w^aM w^aRM (Bhadra et al., 1997, Bhadra et al., 1997, Csink et al., 1994, Rabinow et al., 1993, Hiebert and Birchler, 1992, Rabinow et al., 1991, Peng and Mount, 1990, Birchler and Hiebert, 1989, Mount et al., 1988, Carbonare and Gehring, 1985, )
Name Synonym	apricot of Mossige
Secondary FlyBase IDs
	FBal0018213
References ( 17 )
Research paper	Bhadra et al., 1997, Mol. Gen. Genet. 254(6): 621--634 A trans-acting modifier causing extensive overexpression of genes in Drosophila melanogaster. [FBrf0094159] Bhadra et al., 1997, Genetics 146(3): 903--917 A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats. [FBrf0094158] Bhadra and Birchler, 1996, Mol. Gen. Genet. 250(5): 601--613 Characterization of a sex-influenced modifier of gene expression and suppressor of position-effect variegation in Drosophila. [FBrf0086910] Birchler et al., 1994, Genetics 137(4): 1057--1070 Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster. [FBrf0074960] Csink et al., 1994, Genetics 136(2): 573--583 Mosaic suppressor, a gene in Drosophila that modifies retrotransposon expression and interacts with zeste. [FBrf0068460] Csink et al., 1994, Genetics 138(1): 153--163 The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles. [FBrf0076540] Rabinow et al., 1993, Genetics 134(4): 1175--1185 Mutations at the darkener of apricot locus modulate transcript levels of copia and copia-induced mutations in Drosophila melanogaster. [FBrf0058584] Hiebert and Birchler, 1992, Genetics 130: 539--545 Dosage compensation of the copia retrotransposon in Drosophila melanogaster. [FBrf0056235] Rabinow et al., 1991, Genetics 129: 463--480 A trans-acting regulatory gene that inversely affects the expression of the white, brown and scarlet loci in Drosophila. [FBrf0054158] Peng and Mount, 1990, Genetics 126: 1061--1069 Characterization of enhancer-of-white-apricot in Drosophila melanogaster. [FBrf0051917] Birchler and Hiebert, 1989, Genetics 122: 129--138 Interaction of the Enhancer of white-apricot with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049880] Birchler et al., 1989, Genes Dev. 3: 73--84 Interaction of the mottler of white with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049829] Rabinow and Birchler, 1989, EMBO J. 8: 879--889 A dosage-sensitive modifier of retrotransposon-induced alleles of the Drosophila white locus. [FBrf0049635] Mount et al., 1988, Genetics 118: 221--234 Partial revertants of the transposable element-associated suppressible allele white-apricot in Drosophila melanogaster: Structures and responsiveness to genetic modifiers. [FBrf0048200] Carbonare and Gehring, 1985, Mol. Gen. Genet. 199: 1--6 Excision of copia element in a revertant of the white-apricot mutation of Drosophila melanogaster leaves behind one long-terminal repeat. [FBrf0043247] Green, 1959, Genetics 44: 1243--1256 Non-homologous pairing and crossing over in Drosophila melanogaster. [FBrf0012636] Mossige, 1953, D. I. S. 27: 59 [New mutants report.] [FBrf0063728]

Allele Dmel\waM

Allele Dmel\w^aM