Allele Dmel\w^aR84h

General Information
Symbol	Dmel\w^aR84h	Species	D. melanogaster
Name		FlyBase ID	FBal0018212
Feature type	allele	Associated gene	Dmel\w

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	spontaneous, IR-hybrid dysgenesis
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	IR-hybrid dysgenesis (Rabinow et al., 1991) spontaneous (Mount et al., 1988)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:2,686,840..2,686,844 (Csink et al., 1994, Rabinow et al., 1991, Bhadra and Birchler, 1996, Bhadra et al., 1997, Bhadra et al., 1997, Rabinow and Birchler, 1989)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	w^a (Mount et al., 1988, Rabinow and Birchler, 1989, Birchler and Hiebert, 1989, Peng and Mount, 1990, Rabinow et al., 1991, Rabinow et al., 1993, Bhadra and Birchler, 1996, Bhadra et al., 1997)
Nature of the lesion	Statement Reference Insertion of a I-element into the 3' LTR of the copia element present in w^a. (Bhadra et al., 1997) I-element insertion into copia 3' LTR. (Bhadra and Birchler, 1996) I-element insertion into copia 3' LTR. (Csink et al., 1994) Insertion of 83bp into the 3' LTR of the w^a copia insert. (Rabinow et al., 1993) Insertion of 83bp in the 3'-LTR of copia. (Hiebert and Birchler, 1992) Insert stated as cause: I{} (Bucheton, 1990) I-element insertion in copia 3' LTR. (Birchler and Hiebert, 1989) Insertion of an I-element into the copia 3' LTR. (Rabinow and Birchler, 1989) An 83 nucleotide insertion generating a 13 nucleotide duplication. (Mount et al., 1988) insertion in copia 3' LTR
Caused by insertion	copia{}w^a (Csink et al., 1994, Rabinow et al., 1991, Bhadra and Birchler, 1996, Bhadra et al., 1997, Bhadra et al., 1997, Rabinow and Birchler, 1989) I{}w^aR84h (Csink et al., 1994, Rabinow et al., 1991, Rabinow and Birchler, 1989, Bhadra and Birchler, 1996, Bhadra et al., 1997, Bhadra et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class
	eye color defective (Bhadra et al., 1997)
Phenotype Manifest In
	pigment cell (Bhadra et al., 1997)
Detailed Description
	Statement Reference Eye colour: mottled, with mw¹.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference w^aR84h has phenotype, enhanceable by E(w^a)¹ (Birchler and Hiebert, 1989, Mount et al., 1988, ) w^aR84h has phenotype, enhanceable by Mow^gamma (Bhadra and Birchler, 1996) w^aR84h has phenotype, enhanceable by mw^3P (Birchler et al., 1989) w^aR84h has phenotype, enhanceable by Rm62^D (Csink et al., 1994) w^aR84h has phenotype, enhanceable by Rm62^Dem (Csink et al., 1994) w^aR84h has phenotype, enhanceable by Rm62^E (Csink et al., 1994) w^aR84h has phenotype, enhanceable by Rm62^F (Csink et al., 1994) w^aR84h has phenotype, enhanceable by Rm62^H (Csink et al., 1994) w^aR84h has phenotype, enhanceable by Rm62^K (Csink et al., 1994) w^aR84h has phenotype, enhanceable by su(f)¹ (Mount et al., 1988, ) w^aR84h has phenotype, enhanceable by Wow^ems1 (Birchler et al., 1994) w^aR84h has phenotype, enhanceable by Wow^hd1 (Birchler et al., 1994) w^aR84h has phenotype, enhanceable by Wow^γb (Birchler et al., 1994) w^aR84h has phenotype, enhanceable by Wow^γe (Birchler et al., 1994)
NOT Enhanced by
Statement Reference w^aR84h has phenotype, non-enhanceable by Low¹ (Bhadra et al., 1997) w^aR84h has phenotype, non-enhanceable by mw^2a (Birchler et al., 1989) w^aR84h has phenotype, non-enhanceable by Ufo¹ (Bhadra et al., 1997)
Suppressed by
Statement Reference w^aR84h has phenotype, suppressible by Doa³ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁴ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁵ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁶ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁷ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁸ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa⁹ (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Doa^HD (Rabinow and Birchler, 1989) w^aR84h has phenotype, suppressible by Inr-a^EMS3 (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^EMS4 (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^EMS5 (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^hd1 (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^γb (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^γc (Rabinow et al., 1991) w^aR84h has phenotype, suppressible by Inr-a^γd (Rabinow et al., 1991)
NOT suppressed by
Statement Reference w^aR84h has phenotype, non-suppressible by Low¹ (Bhadra et al., 1997) w^aR84h has phenotype, non-suppressible by su(w^a)^unspecified (Mount et al., 1988, ) w^aR84h has phenotype, non-suppressible by Ufo¹ (Bhadra et al., 1997)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Mossige.
	Revertant. \strong
Comments
	I-element insertion in copia 3' LTR of w^a. (Rabinow et al., 1991)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	w^aR84h
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Bhadra et al., 1997, Genetics 146(3): 903--917 A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats. [FBrf0094158] Bhadra et al., 1997, Mol. Gen. Genet. 254(6): 621--634 A trans-acting modifier causing extensive overexpression of genes in Drosophila melanogaster. [FBrf0094159] Bhadra and Birchler, 1996, Mol. Gen. Genet. 250(5): 601--613 Characterization of a sex-influenced modifier of gene expression and suppressor of position-effect variegation in Drosophila. [FBrf0086910] Birchler et al., 1994, Genetics 137(4): 1057--1070 Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster. [FBrf0074960] Csink et al., 1994, Genetics 138(1): 153--163 The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles. [FBrf0076540] Rabinow et al., 1993, Genetics 134(4): 1175--1185 Mutations at the darkener of apricot locus modulate transcript levels of copia and copia-induced mutations in Drosophila melanogaster. [FBrf0058584] Hiebert and Birchler, 1992, Genetics 130: 539--545 Dosage compensation of the copia retrotransposon in Drosophila melanogaster. [FBrf0056235] Rabinow et al., 1991, Genetics 129: 463--480 A trans-acting regulatory gene that inversely affects the expression of the white, brown and scarlet loci in Drosophila. [FBrf0054158] Peng and Mount, 1990, Genetics 126: 1061--1069 Characterization of enhancer-of-white-apricot in Drosophila melanogaster. [FBrf0051917] Birchler and Hiebert, 1989, Genetics 122: 129--138 Interaction of the Enhancer of white-apricot with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049880] Birchler et al., 1989, Genes Dev. 3: 73--84 Interaction of the mottler of white with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049829] Rabinow and Birchler, 1989, EMBO J. 8: 879--889 A dosage-sensitive modifier of retrotransposon-induced alleles of the Drosophila white locus. [FBrf0049635] Mount et al., 1988, Genetics 118: 221--234 Partial revertants of the transposable element-associated suppressible allele white-apricot in Drosophila melanogaster: Structures and responsiveness to genetic modifiers. [FBrf0048200] Mount and Rubin, 1985, Mol. Cell. Biol. 5(7): 1630--1638 Complete nucleotide sequence of the Drosophila transposable element copia: homology between copia and retroviral proteins. [FBrf0043227]
Review	Bucheton, 1990, Trends Genet. 6(1): 16--21 I transposable elements and I-R hybrid dysgenesis in Drosophila. [FBrf0053032]

Allele Dmel\waR84h

Allele Dmel\w^aR84h