Allele Dmel\w^zl

General Information
Symbol	Dmel\w^zl	Species	D. melanogaster
Name	zeste light	FlyBase ID	FBal0018325
Feature type	allele	Associated gene	Dmel\w

Allele class
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	spontaneous (Judd, 1995)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	w^zm (Birchler and Hiebert, 1989, Peterson et al., 1994, Judd, 1995)
Nature of the lesion	Statement Reference Insertion of a 1.8kb transposon into the 5' untranslated leader of w. (Judd, 1995) Derivative of w^zl. (Csink et al., 1994) Insertion of an additional 1.8kb transposon, with 82bp inverted repeats, at coordinate +4.27, the 3S18 insertion is unmodified. (Peterson et al., 1994)
Cytology
Phenotypic Data
Phenotypic Class
	eye color defective visible \| recessive
Phenotype Manifest In
	pigment cell (Kalisch and Rasmuson, 1974)
Detailed Description
	Statement Reference Eye colour: wild-type, in z⁺ males or females. Eye colour: large patches of red on yellow background, in z¹ male. Eye colour: occasional red mottling, in z¹ female. Eye colour: lighter yellow background as z^v77h w^zl male, compared with z¹ w^zl male. (Judd, 1995) Eye colour: wild-type, as homozygous z⁺ w^zm female. (Peterson et al., 1994) Eye colour: variegated, as homozygous z⁺ w^zm female. (Kalisch and Rasmuson, 1974) Eye colour: lemon yellow, in z¹ w^zl female at 25^oC-30^oC. Eye colour: yellow eyes with large red spots, as z¹ w^zl female at 14^oC. Eye colour: yellow eyes with large red spots, as z¹ w^zl male at 25^oC-30^oC. Eye colour: red spots on yellow with salt-and-pepper mottling, as z¹ w^zl male at 14^oC.
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference w^zl has phenotype, enhanceable by Wow^ems1 (Birchler et al., 1994) w^zl has phenotype, enhanceable by Wow^hd1 (Birchler et al., 1994) w^zl has phenotype, enhanceable by Wow^γb (Birchler et al., 1994) w^zl has phenotype, enhanceable by Wow^γe (Birchler et al., 1994)
NOT Enhanced by
Statement Reference w^zl has phenotype, non-enhanceable by E(w^a)¹ (Birchler and Hiebert, 1989) w^zl has phenotype, non-enhanceable by In(3)Msu¹ (Csink et al., 1994) w^zl has phenotype, non-enhanceable by In(3)Msu² (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^D (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^Dem (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^E (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^F (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^H (Csink et al., 1994) w^zl has phenotype, non-enhanceable by Rm62^K (Csink et al., 1994)
Suppressed by
Statement Reference w^zl has phenotype, suppressible by E(z)⁶⁰ (Peterson et al., 1994)
NOT suppressed by
Statement Reference w^zl has phenotype, non-suppressible by In(3)Msu¹ (Csink et al., 1994) w^zl has phenotype, non-suppressible by In(3)Msu² (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^D (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^Dem (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^E (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^F (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^H (Csink et al., 1994) w^zl has phenotype, non-suppressible by Rm62^K (Csink et al., 1994)
Additional Comments
Genetic Interactions
Statement Reference Eye colour: yellow with red patches, as hemizygous z¹ w^zl male. Eye colour: yellow, as homozygous z¹ w^zl female. Slightly suppressed in z¹ w^zl, with a darkening of the background eye colour. (Peterson et al., 1994)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Becker, 1958. H.J. Becker.

Comments
	Insertion of the unknown transposon is unstable and has spontaneously deleted. (Peterson et al., 1994) The change is located to the right of w^a and probably also to the right of w^ch. (Judd, 1965)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	w^zl
Name Synonym	zeste light (Judd, 1965, )
Secondary FlyBase IDs

References ( 13 )
Research paper	Judd, 1995, Genetics 141(1): 245--253 Mutations of zeste that mediate transvection are recessive enhancers of position-effect variegation in Drosophila melanogaster. [FBrf0084074] Birchler et al., 1994, Genetics 137(4): 1057--1070 Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster. [FBrf0074960] Csink et al., 1994, Genetics 138(1): 153--163 The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles. [FBrf0076540] Csink et al., 1994, Genetics 136(2): 573--583 Mosaic suppressor, a gene in Drosophila that modifies retrotransposon expression and interacts with zeste. [FBrf0068460] Peterson et al., 1994, Mol. Gen. Genet. 242(6): 717--726 The determined state of white expression in the Drosophila eye is modified by zeste¹ in the w^zm family of mutants. [FBrf0068635] Birchler and Hiebert, 1989, Genetics 122: 129--138 Interaction of the Enhancer of white-apricot with transposable element alleles at the white locus in Drosophila melanogaster. [FBrf0049880] Kalisch and Rasmuson, 1974, Hereditas 78: 97--104 Changes of zeste phenotype induced by autosomal mutations in Drosophila melanogaster. [FBrf0026500] Judd, 1965, D. I. S. 40: 35 [New mutants report.] [FBrf0095371] Judd, 1964, D. I. S. 39: 59--60 [New mutants report.] [FBrf0063553] Becker, 1960, Genetics 45(5): 519--534 Variegation in the zeste eye color alleles and its bearing on gene action during the development of the eye of Drosophila melanogaster. [FBrf0013333] Becker, 1959, D. I. S. 33: 82 [New mutants report.] [FBrf0063300]
Review	Green, 1976, Ashburner, Novitski, 1976 b: 929--946 Mutable and mutator loci. [FBrf0028345]
Abstract	Judd, 1963, Int. Congr. Genet. 11 1: 3--4 The genetic fine structure of the mutants z^m and z^l in Drosophila melanogaster. [FBrf0015495]

Allele Dmel\wzl

Allele Dmel\w^zl