wg1/wgl-17 and wg1/wgGBM, but not wg1/+, larvae have significantly reduced bouton number and significantly increased bouton size at the neuromuscular junction of muscle 4, compared to controls.
In a significant proportion of wg1 homozygotes, adults show transformation of one or both wings into notum and third instar larvae present wing discs with presumptive wing tissue replaced by notum tissue; these adults also present decreased wing regeneration capacity, as shown by the significant decrease in the number of adults with fully regenerated wings following rpr-induced damage to the third instar wing disc pouch, as compared to wild-type controls.
A minority of wg1/+ flies have at least one wing transformed into notum.
wg1/wgl-12 flies show loss of indirect flight muscles.
wg1/wgl-17 mutants display a wing-to-notum transformation.
Homozygous wg1 larvae do not show the increase in ghost bouton formation seen in controls upon spaced 5X K[+] depolarisation.
Homozygotes show a wing to notum transformation.
wg1/wg17en40cP1 wing discs show replacement of wing by a duplication of notum structures, which is also seen in the adult flies.
wg1/wgl-17 flies exhibit ectopic notum and have no wings.
25% of wg1/wgP flies have wings on the prothoracic segment, and mesothoracic wings and metathoracic halteres develop variably.
wg wing phenotype. Individuals are adult viable and exhibit the wing phenotype when in combination with wgSp-revP, wgl-17, wgl-16 or wgP. Individuals are wild type when in combination with wgSp-1 and wgspd-j2.
Flies often lack wings and show a symmetric duplication of body wall structures.
Semiviable, deletion of the ventralmost part of the eye. Ectopic furrow movement initiates predominantly from the ventral margin.
N, wg1 and arm4 triple mutants display, with about 10-20% penetrance, a perfect duplication of the notum charcateristic of wg mutations.
Additional bristles present on the second leg.
Flies exhibit a variable loss of one or two wings.
Adult homeotic transformation of wing to notum.
Phenotype shows incomplete penetrance and expressivity; 50.8% of flies have no wings, 40.67% have one wing, and 8.47% have two wings.
The progeny of wg1 parents are composed of flies with no wings, one wing and two wings in approximately 2:2:1 ratio. wg1 flies may also have no, one, or both halteres. The two phenotypes are independent of each other as mutants can be found that have wings but no halteres, and vice versa.