Allele Dmel\y^3d

General Information
Symbol	Dmel\y^3d	Species	D. melanogaster
Name	3 dark	FlyBase ID	FBal0018616
Feature type	allele	Associated gene	Dmel\y

Allele class	hypomorphic allele - genetic evidence
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Drapeau et al., 2006)
Mutagen	spontaneous (Chia et al., 1986, Morris et al., 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference 7kb insertion 5' to the start of transcription, within the 489bp HindIII/BalI fragment. (Chia et al., 1986)
Caused by insertion	?{}y^3d (Chia et al., 1986)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective (Drapeau et al., 2006, Chia et al., 1986) mating defective \| male (Drapeau et al., 2006)
Phenotype Manifest In
	adult (Drapeau et al., 2006) adult cuticle (Chia et al., 1986) arista (Drapeau et al., 2006) chaeta (Drapeau et al., 2006) embryonic/larval mouth (Drapeau et al., 2006)
Detailed Description
	Statement Reference y^3d males have significantly reduced mating success compared to control males. The Dp(1;f)1187 minichromosome rescues the mating success of these mutants. y^3d adults show a reduction in pigmentation on the body, bristles and arista. The tarsal claws show a moderate decrease in pigmentation. However, wings are the normal grey colour. Larval mouth-part pigmentation is reduced. (Drapeau et al., 2006) Body colour: type 2 allele - some areas of cuticle are wild type, others have mutant pigmentation. (Chia et al., 1986) Body colour: body, bristles, yellow; wings grey. Larval mouth part colour: yellow; hooks, light.
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially complements	y² (Morris et al., 1999) y^62a (Morris et al., 1999) y^82f29 (Morris et al., 1999) y²³⁷⁴ (Morris et al., 1999)
Fails to complement	y^59b (Morris et al., 1999)
Comments
Stocks ( 1 )
Bloomington	195 y^3d/C(1)DX, y¹ f¹
Notes on Origin
Discoverer	Sturtevant, 1933.

Comments
	Allelic series of reduced male mating success phenotype: y^59b = y^D91 >= y^3d > y^a77 >= y^2S. (Drapeau et al., 2006)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	y^3d
Name Synonym	3 dark
Secondary FlyBase IDs

References ( 8 )
Research paper	Drapeau et al., 2006, Genetics 172(2): 1009--1030 A cis-regulatory sequence within the yellow locus of Drosophila melanogaster required for normal male mating success. [FBrf0190716] Morris et al., 1999, Genetics 151(2): 633--651 An analysis of transvection at the yellow locus of Drosophila melanogaster. [FBrf0106981] Walter et al., 1991, Dev. Biol. 147(1): 32--45 Temporal and spatial expression of the yellow gene in correlation with cuticle formation and dopa decarboxylase activity in Drosophila development. [FBrf0053728] Chia et al., 1986, EMBO J. 5: 3597--3605 Molecular analysis of the yellow locus of Drosophila. [FBrf0044248] Biessmann, 1985, Proc. Natl. Acad. Sci. U.S.A. 82: 7369--7373 Molecular analysis of the yellow gene (y) region of Drosophila melanogaster. [FBrf0043479] Nash, 1976, Dev. Biol. 48: 336--343 Patterns of pigmentation color states regulated by the y locus in Drosophila melanogaster. [FBrf0028555] Nash and Yarkin, 1974, Genet. Res. (Camb.) 24: 19--26 Genetic regulation and pattern formation: A study of the yellow locus in Drosophila melanogaster. [FBrf0026311] Brehme, 1941, Proc. Natl. Acad. Sci. U.S.A. 27: 254--261 The effect of adult body color mutations upon the larva of Drosophila melanogaster. [FBrf0005535]

Allele Dmel\y3d

Allele Dmel\y^3d