A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Allele Dmel\Abd-B05649

General Information
SymbolDmel\Abd-B05649SpeciesD. melanogaster
NameFlyBase IDFBal0019069
Feature typealleleCreated / Updated2006-05-14/2006-05-14
Associated geneDmel\Abd-B
Allele class
MutagenP-element activity
hide Nature of the Allele
Allele class
Mutagen
P-element activity
(Castrillon et al., 1993)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      P{PZ} insertion within the iab-7 domain, immediately adjacent to the minimal Fab-8 insulator.
      (Zhou and Levine, 1999)
      Assay mode
      Caused by insertion
      P{PZ}Abd-B05649
      (Castrillon et al., 1993, Zhou and Levine, 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999, Bellen et al., 2004, Barges et al., 2000)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      visible | homeotic (with Df(3R)Abd-BS10)
      (Zhou and Levine, 1999)
      female sterile
      (Castrillon et al., 1993)
      female sterile | recessive
      (Spradling et al., 1999)
      male sterile
      (Castrillon et al., 1993)
      hide Phenotype Manifest In
      anal plate
      (Castrillon et al., 1993)
      abdominal tergite 7 (with Df(3R)Abd-BS10)
      (Zhou and Levine, 1999)
      abdominal tergite 5 (with Df(3R)Abd-BS10)
      (Zhou and Levine, 1999)
      abdominal tergite 5 & trichome (with Df(3R)Abd-BS10)
      (Zhou and Levine, 1999)
      hide Detailed Description
      Statement
      Reference
      Anal plate twisted in both males and females.
      (Castrillon et al., 1993)
      Heterozygous adult males show a normal segmentation pattern in the abdomen. Abd-B05649/Df(3R)Abd-BS10 males show abdominal transformations; the A7 tergite is fully developed in these animals, indicating a transformation towards an A5/A6 identity. In addition, the A5 tergite is partially transformed towards A4, as indicated by a partial loss of pigment in anterior regions and by the trichome pattern.
      (Zhou and Levine, 1999)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 0 )
      hide Notes on Origin
      Discoverer
      A. Spradling.
      hide Synonyms & Secondary IDs ( 7 )
      Reported As
      Symbol Synonym
      Abd-B05649
       
      fs(3)05649
      (Bellen et al., 2004, Spradling et al., 1999, )
      fs(3)5649
      (Barges et al., 2000, Zhou and Levine, 1999)
      iab-7p302
      (Zhou and Levine, 1999)
      ms(3)05649
       
      twig1
      (Castrillon et al., 1993, )
      twig05649
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 6 )
        Research paper
        Bellen et al., 2004, Genetics 167(2): 761--781
        The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. [FBrf0179132]
        Barges et al., 2000, Development 127(4): 779--790
        The fab-8 boundary defines the distal limit of the Bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain. [FBrf0125451]
        Spradling et al., 1999, Genetics 153(1): 135--177
        The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
        Zhou and Levine, 1999, Cell 99(6): 567--575
        A novel cis-regulatory element, the PTS, mediates an anti-insulator activity in the Drosophila embryo. [FBrf0123260]
        Castrillon et al., 1993, Genetics 135(2): 489--505
        Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. [FBrf0064394]
        Computer file
        BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
        Berkeley Drosophila Genome Project. [FBrf0067338]