FB2025_01 , released February 20, 2025
Allele: Dmel\cuc1
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General Information
Symbol
Dmel\cuc1
Species
D. melanogaster
Name
FlyBase ID
FBal0028138
Feature type
allele
Associated gene
cuc
Associated Insertion(s)
P{PZ}cuc1
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Castrillon et al., 1993)
Progenitor genotype
Associated Insertion(s)
P{PZ}cuc1
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Survival to adulthood is reduced in Df(2L)mir-275-305KO/cuc1 mutants and the life span of adult flies is short compared with controls. They also show an extra bristle phenotype.

      (Foronda et al., 2014)

      Males cannot court or mate females. Longevity of males and females is decreased.

      (Castrillon et al., 1993)

      male semi-sterile. Males fail to court and mate females. Longevity of males and females decreased.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: mts02496. Complements: l(2)37Ad02660b. Complements: Bsg06243. Complements: l(2)rL220rL220. Complements: Bsggel.

      (BDGP Project Members, 1994-1999)

      mir-275 and mir-305 miRNAs are reduced to low levels in cuc1/Df(2L)mir-275-305KO animals, indicating cuc1 is a mir-275-mir-305 allele.

      (Foronda et al., 2014)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      cuc05158
      cuc1
      (Foronda et al., 2014)
      ms(2)05158
      (Beaton, 1999.12.12, Spradling et al., 1999)
      ms(2)0515805158
      Name Synonyms
      Secondary FlyBase IDs
        References (7)