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General Information
Symbol
Dmel\Su(z)25
Species
D. melanogaster
Name
FlyBase ID
FBal0028573
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Deletion extends from 3' flanking sequences of the vg locus.
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
One copy of Su(z)25 is unable to suppress position effect variegation (PEV) at the w locus caused by In(1)wm4. One copy of Su(z)25 strongly suppresses the telomeric position effect (TPE) in stocks carrying a variegating P{hsp26-pt-T}39C-5 insertion at the telomere of the left arm of chromosome two.
Su(z)25/+ suppresses the telomeric position effect (TPE) of P{hsp26-pt-T}39C-5, P{hsp26-pt-T}39C-27, P{hsp26-pt-T}39C-31 and P{wA}4-4.
Has little effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males, but acts as a meiotic drive suppressor, suppressing drive against the X and Y chromosomes in these flies.
Su(z)25 can show a strong dominant suppression on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w+mW.hs allele at the telomeres of the second and third chromosome. Has no effect on pericentric and fourth chromosome insertions. Su(z)25 suppresses the telomeric Position effect variegation (PEV) of P{hsp26-pt-T}39C-50, P{hsp26-pt-T}39C-58, P{hsp26-pt-T}39C-31, P{hsp26-pt-T}39C-51, P{hsp26-pt-T}39C-62, P{hsp26-pt-T}118E-16, P{hsp26-pt-T}118E-26, P{hsp26-pt-T}118E-21, P{hsp26-pt-T}39C-27 and P{hsp26-pt-T}39C-5.
No homeotic phenotype. Cannot enhance the homeotic phenotypes of Pc group mutants (FBrf0049524).
In z1 wzm strain mutation causes reduction of eye pigmentation. Slightly suppress w phenotype in a e(y) background.
Sensitive to aminopterin.
zeste-->yellow-orange eyes
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Su(z)25 is an enhancer of visible phenotype of ctpN2s
Su(z)25 is an enhancer of visible phenotype of ctn2s
Suppressor of
Statement
Reference
Su(z)25 is a suppressor of eye color defective phenotype of z1
Phenotype Manifest In
Enhancer of
Statement
Reference
Su(z)25 is an enhancer of wing phenotype of ctpN2s
Su(z)25 is an enhancer of wing phenotype of ctn2s
Suppressor of
Statement
Reference
Su(z)25 is a suppressor of phenotype of z1
Additional Comments
Genetic Interactions
Statement
Reference
The addition of Su(z)25 suppresses the Pairing sensitive silencing effect seen inwMcp.y.scs'.1 and strongly suppresses the eye colour phenotype of double insertion combinations of wMcp.scs'.21/ywe.Mcp.1 (P{Mcp-w#21}124/+, P{Mcp-wy#1}183/+) and wMcp.y.scs'.1/ywe.Mcp.2 (P{Mcp-yw#1}103/+, P{Mcp-wy#2}50/+). The addition of Su(z)25 has no effect on the Pairing sensitive silencing effect seen in wMcp.scs'.21.
Has no effect on the phenotypes of ct2s, ct4s and ct6, where the wing margin enhancer is completely blocked.
Dominant suppressor of z1 eye color: eye color is more wild type. Eye color of heterozygous females which are also z1/z1 : orange (with speckling). Eye color of heterozygous males which are also z1, wis/Y: maroon (with subtle speckling).
Heterozygous flies modify the yellow eyes of z1 to yellow orange: dominant suppressors of z1 eye colour.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Wu.
Comments
Comments
Lethal when heterozygous with Psc1.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
  • FBal0013985
References (19)