The structure of the Golgi and cell polarity are not affected in Arl11 cell clones.
Arl11 clones in the wing disc show increased apoptosis. This phenotype is not seen in follicle cell or salivary gland clones.
Arl12/Arl11 larval salivary glands have more secretory granules of significantly smaller size, compared to controls.
Arf72A1 cells within a mutant retinal clone show proliferated internal membranes. Most strikingly, rough endoplasmic reticulum-type membranes are greatly expanded, swollen and have more pronounced heterogeneity compared to wild type.
Arf72A1 eye cells have extensive Golgi structures both in size and number throughout the cytoplasm compared to wild type.
Centrosome maturation proceeds normally in most mutant embryos through the early syncytial blastoderm but a low percentage of centrosomes are either small or fused. During the late syncytial blastoderm stage, the number of centrosome and nuclear fusions increases. Approximately 63% of embryos complete cellularization and initiate gastrulation prior to failure, but furrow- and segment-formation is weak or incomplete, giving the cortex a smooth, flat appearance. Mitotic domains have fewer cells than in wild type and many spindles have a single centrosome. The nuclear density is low in these embryos and many nuclei appear to be aneuploid.