FB2025_01 , released February 20, 2025
Allele: Dmel\BicCPX1
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General Information
Symbol
Dmel\BicCPX1
Species
D. melanogaster
Name
FlyBase ID
FBal0029052
Feature type
allele
Associated gene
Dmel\BicC
Associated Insertion(s)
Carried in Construct
Also Known As
Bic-CPX1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12, Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most eggs laid develop to hatched larvae, some eggs are undeveloped due to a developmental block in the later syncytial divisions. Oogenesis does not proceed beyond early stage 10 in ovaries from homozygous females due to a defect in the central migration of the anterior columnar follicle cells.

      (Mahone et al., 1995)

      Dominant haplo-insufficiency phenotype, eggs produced have fused dorsal appendages.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Bic-CPX1
      (Saffman et al., 1998, Mahone et al., 1995)
      BicCPX1
      Name Synonyms
      Secondary FlyBase IDs
        References (4)