Allele Dmel\Hdc^P218

General Information
Symbol	Dmel\Hdc^P218	Species	D. melanogaster
Name		FlyBase ID	FBal0029840
Feature type	allele	Associated gene	Dmel\Hdc

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	visual behavior defective \| recessive (Burg et al., 1993)
Phenotype Manifest In
	retina (Burg et al., 1993)
Detailed Description
	Statement Reference On/off transients of ERG are reduced. (Burg et al., 1993)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Induced by chemical mutagenesis. Mutants consistently show very low levels (10-fold less than wild type) of histamine synthesis. (Burg et al., 1993)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	hdc^P218 (Melzig et al., 1998, Sarthy et al., 1991, Burg et al., 1993) Hdc^P218 (Rahman et al., 2012)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Rahman et al., 2012, Nat. Neurosci. 15(6): 871--875 Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections. [FBrf0219393] Melzig et al., 1998, J. Neurosci. 18(18): 7160--7166 Selective histamine uptake rescues photo- and mechanoreceptor function of histidine decarboxylase-deficient Drosophila mutant. [FBrf0104486] Burg et al., 1993, EMBO J. 12(3): 911--919 Genetic and molecular identification of a Drosophila histidine decarboxylase gene required in photoreceptor transmitter synthesis. [FBrf0058167]
Abstract	Sarthy et al., 1991, Greenspan, Palka, 1991: 159 Characterization of mutants blocked in synaptic transmitter synthesis in Drosophila photoreceptors. [FBrf0079321]

Allele Dmel\HdcP218

Allele Dmel\Hdc^P218