Allele Dmel\Inr-a^hd1

General Information
Symbol	Dmel\Inr-a^hd1	Species	D. melanogaster
Name		FlyBase ID	FBal0029866
Feature type	allele	Associated gene	Dmel\Inr-a

Allele class	loss of function allele
Mutagen	PM hybrid dysgenesis
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	loss of function allele (Rabinow et al., 1991)
Mutagen	PM hybrid dysgenesis (Rabinow et al., 1991)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Point mutation in the consensus splicing donor site of intron 4, resulting in the production of a truncated transcript. (Xie and Birchler, 2012)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| larval stage \| recessive (Rabinow et al., 1991)
Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference Inr-a^hd1 is a suppressor of phenotype of w^a2 (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^a3 (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^a4 (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^a59k1 (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^a (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^aM (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^aR84h (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^bf (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^bl (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^Bwx (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^cf (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^col (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^h (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^IR2 (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^IRI (Rabinow et al., 1991) Inr-a^hd1 is a suppressor of phenotype of w^sat (Rabinow et al., 1991)
NOT Suppressor of
Statement Reference Inr-a^hd1 is a non-suppressor of phenotype of w^apl (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^c (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^e (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of wⁱ (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^sp1 (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^sp2 (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^sp4 (Rabinow et al., 1991) Inr-a^hd1 is a non-suppressor of phenotype of w^sp81d (Rabinow et al., 1991)
Additional Comments
Genetic Interactions
Statement Reference Darkens eye colour: elevation of pigment levels of w^a, and darker Malpighian tubules and testes. (Rabinow et al., 1991)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	Inr-a^k08015 (Xie and Birchler, 2012)
Comments	Inr-a[k08015] fails to complement the recessive lethality of Inr-a[hd1]. (Xie and Birchler, 2012)
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Stable mutation that cannot be reverted by P element transposase with P{Δ2-3}. (Rabinow et al., 1991)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Inr-a^hd1 (Xie and Birchler, 2012)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Xie and Birchler, 2012, G3 (Bethesda) 2(6): 701--706 Identification of Inverse Regulator-a (Inr-a) as Synonymous with Pre-mRNA Cleavage Complex II Protein (Pcf11) in Drosophila. [FBrf0218562] Rabinow et al., 1991, Genetics 129: 463--480 A trans-acting regulatory gene that inversely affects the expression of the white, brown and scarlet loci in Drosophila. [FBrf0054158]

Allele Dmel\Inr-ahd1

Allele Dmel\Inr-a^hd1