Allele Dmel\Pgm^4tr

General Information
Symbol	Dmel\Pgm^4tr	Species	D. melanogaster
Name		FlyBase ID	FBal0030032
Feature type	allele	Associated gene	Dmel\Pgm
Also Known As	Pgm^1.00,tr,6.1

Allele class
Mutagen	natural population
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	natural population (Cicchetti et al., 1991)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Carried on aberration	TM3-ISPSAS (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
Cytology
Phenotypic Data
Phenotypic Class
	electrophoretic variant (Bubli et al., 1996, Cicchetti et al., 1991)
Phenotype Manifest In

Detailed Description
	Statement Reference codominant Enzyme is temperature-resistant (Trippa et al., 1976; Trippa et al., 1978). Pgm^4tr and Pgm^4ts together account for 79.3 - 99.2% allele frequency in natural populations of Puglia and Sicily (Trippa et al., 1972).
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	4018 Idh^F Sod^F Pgm^6tr Ald²/TM3, Idh^S Sod^S Pgm^4tr Sb¹ Ald⁴ Ser¹
Kyoto	107557 Idh^F Sod^F Pgm^6tr Ald²/TM3, Idh^S Sod^S Pgm^4tr Sb¹ Ald⁴ Ser¹
Notes on Origin
Discoverer

Comments
	Results from a series of reciprocal crosses demonstrate that the isoelectric point is a specific property of the protein and is under genetic control. The isoelectric point is 6.1. (Cicchetti et al., 1990) Estimated gene frequency is 83.2 to 90.7% in Castellaneta and Ranna populations. (Trippa et al., 1976)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	1.00 (Bubli et al., 1996) Pgm^1.00,tr,6.1 (Cicchetti et al., 1991, Cicchetti et al., 1990) Pgm^1.00,tr (Trippa et al., 1978) Pgm^1.00 Pgm¹ Pgm^4tr Pgm^A (Trippa et al., 1976, )
Name Synonym
Secondary FlyBase IDs

References ( 12 )
Research paper	Bubli et al., 1996, Heredity 77(6): 638--645 Variation of allozyme loci in populations of Drosophila melanogaster from the former USSR. [FBrf0091023] Cicchetti et al., 1991, D. I. S. 70: 49 A new allele at the PGM locus in Drosophila melanogaster, detected by isoelectric-focusing (IEF). [FBrf0053687] Cicchetti et al., 1990, Biochem. Genet. 28: 247--255 Investigations on the PGM (phosphoglucomutase) polymorphism by isoelectric focusing in Drosophila melanogaster. [FBrf0051219] Trippa et al., 1978, Biochem. Genet. 16(3/4): 299--305 A simple approach for discovering common nonelectrophoretic enzyme variability: a heat denaturation study in Drosophila melanogaster. [FBrf0031062] Trippa et al., 1977, D. I. S. 52: 74 A new allele at the Pgm locus in D. melanogaster. [FBrf0029927] Trippa et al., 1976, Nature 260: 42--44 Thermostability studies for investigating non-electrophoretic polymorphic alleles in Drosophila melanogaster. [FBrf0029278] Trippa et al., 1972, D. I. S. 49: 35 Phosphoglucomutase ^C,D,E,F. [FBrf0023619] Trippa et al., 1972, D. I. S. 49: 42--43 Phosphoglucomutase (pgm) polymorphism in natural population of Drosophila melanogaster. [FBrf0023624] Hjorth, 1970, D. I. S. 45: 39 [New mutants report.] [FBrf0063518] Trippa et al., 1970, Biochem. Genet. 4: 665--667 Phosphoglucomutase (PGM) locus in Drosophila melanogaster: linkage and population data. [FBrf0021150]
Personal communication to FlyBase	Bloomington Drosophila Stock Center, 2001.8.28, Balancer Variants. Balancer Variants. [FBrf0138610]
FlyBase analysis	FlyBase Curators, 2006-, Balancer summary information. Balancer summary information. [FBrf0189689]

Allele Dmel\Pgm4tr

Allele Dmel\Pgm^4tr