Ras85D^e1B/+ rescues the lifespan defect of Uba1^B1/+ mutants, and partially rescues the lifespan defect of Uba1^B1/Uba1^B1 mutants.

(Liu and Pfleger, 2013)

Ras85D^e1B suppresses the increased size of Apc2^g10 Apc^Q8 mutant intestinal stem cell clones 7 and 14 days after clone induction (ACI). The multilayering phenotype often seen at 21 days ACI is also suppressed. This reduction in cell number is due to reduced proliferation, rather than increased cell death: TUNEL expression is unchanged and expression of the apoptotic protein BacA\p35 has no effect on the phenotype. The remaining increase in clone size seen in the Ras85D^e1B, Apc2^g10, Apc^Q8 triple mutant flies is fully suppressed upon expression of pan^ΔN.Scer\UAS under the control of Scer\GAL4^Act.PU, and no increase in apoptosis is seen in these flies.

(Wang et al., 2013)

The extra wing vein phenotype caused by expression of CG4096^KK108644 under the control of Scer\GAL4^Act5C.PU is significantly suppressed if the flies also carry Ras85D^e1B.

(Butchar et al., 2012)

Ras85D^e1B flies which are also expressing Bap170^C1.Scer\UAS under the control of Scer\GAL4^hs.2sev have rough eyes and lack all R7 photoreceptor cells.

(Rendina et al., 2010)

Ras85D^e1B dominantly suppresses the extra wing veins caused by constitutive expression of Rabex-5^VDRC.cUa via Scer\GAL4^Act.PU. Ras85D^e1B dominantly suppresses the extra wing veins caused by wing-specific expression of Rabex-5^VDRC.cUa via Scer\GAL4^C-765. A Ras85D^e1B/+ genetic background results in fewer flies with severe eye phenotypes upon co-expression of Rabex-5^VDRC.cUa and Dcr-2^Scer\UAS.cDa driven by Scer\GAL4^ey.PU. Ras85D^e1B dominantly suppresses the increased body size, body length and wing area resulting from the expression of Rabex-5^VDRC.cUa driven by Scer\GAL4^Act.PU. Body weight of all flies and wing area in female flies are no longer statistically different from controls.

(Yan et al., 2010)

The presence of a Ras85D^e1B background significantly suppresses ectopic wing vein formation found in csw^{Y279C.Scer\UAS} (Scer\GAL4^tub) mutants. A Ras85D^e1B background suppresses the csw^{Y279C.Scer\UAS} (Scer\GAL4^tub) rough eye phenotype, normalizing the numbers of R7 and ommatidial rotation.

(Oishi et al., 2009)

The cell-autonomous overgrowth phenotype found in Uba1^B2 homozygous and Uba1^B1/Uba1^B2 trans-heterozygous eye discs is suppressed in a Ras85D^e1B heterozygous background. A Ras85D^e1B/+ background dramatically suppresses the lethality found in Uba1^B1/Uba1^B2 homozygotes. Uba1^B1/Uba1^B2 eyes in a Ras85D^e1B heterozygous background show decreased suppression of egr^Scer\UAS.cMa (under the control of Scer\GAL4^GMR.PF) induced cell death. Overall cell proliferation in Uba1^B1/Uba1^B2 eye discs is reduced in a Ras85D^e1B/+ background. Ectopic proliferation posterior to the morphogenetic furrow decreases and is restricted to a thin stripe. A Ras85D^e1B/+ background dramatically suppresses the non-autonomous overgrowth phenotype found in Uba1^A1 mosaic eye clones.

(Yan et al., 2009)

Expression of S6kII^{K231R.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^hs.2sev, causes a more severe loss of photoreceptor cells when expressed in a Ras85D^e1B/+ background. Expression of S6kII^{Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^GMR.PF, causes a more severe roughened-eye phenotype and a greater loss of rhabdomeres when expressed in a rl^10a/+ background than when expressed in a wild-type background.

(Kim et al., 2006)

The ectopic wing vein phenotype caused by expression of Socs44A^Scer\UAS.cRa under the control of Scer\GAL4^en-e16E is suppressed by Ras85D^e1B/+.

(Rawlings et al., 2004)

Ras85D^e1B/+, S⁰⁵⁶⁷¹/+ double mutants have a stronger missing-bract phenotype than either mutant alone. (2% of bracts in the tibia and 60% in the basitarsus of the second leg remain). The addition of Ras85D^hs.M11.2 under heat shock control partially suppresses this phenotype.

(Held, 2002)

Ras85D^e1B/+ significantly restores the organisation of cysts and membrane deposition in the testes of homozygous Df(3R)rn20 males. These animals show reduced eclosion and have a short life span. Ras85D^e1B/+ in a Df(3R)rn20 homozygous background results in a significant increase in the number of pigment cells and closer packing than seen in a Df(3R)rn20 single mutant background. The ommatidia remain strangely shaped and have variable numbers of outer and inner photoreceptor cells. There is a drastic reduction in the depth of the retina.

(Bergeret et al., 2001)

Strongly enhances the eye phenotype produced by activated arm constructs. (either arm^S44Y.GMR or arm^S56F.GMR).

(Freeman and Bienz, 2001)

Expression of both Tsc1^Scer\UAS.cTa and gig^Scer\UAS.cTa in the eye under the control of Scer\GAL4^ey.PH results in a much smaller eye than normal. Addition of one copy of Ras85D^e1B enhances the phenotype.

(Tapon et al., 2001)

Dominantly suppresses the eye phenotype caused by C3G^{Scer\UAS.T:Hsap\MYC,T:Ggal\Myr3} expressed under the control of Scer\GAL4^GMR.PF. Completely dominantly suppresses the wing vein phenotype caused by C3G^{Scer\UAS.T:Hsap\MYC,T:Ggal\Myr3} expressed under the control of Scer\GAL4^dpp.blk1.

(Ishimaru et al., 1999)

Enhances the phenotype of E2f^GMR.PD Dp^GMR.PD BacA\p35^GMR.PH flies.

(Staehling-Hampton et al., 1999)

Dominantly suppresses the ability of Src42A^Su(phl)1-1 to suppress the lethality of phl¹/Y flies.

(Zhang et al., 1999)

The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is suppressed by Ras85D^e1B.

(Maixner et al., 1998)

pb^hs.PB Ras85D^e1B double heterozygotes have a partially penetrant truncation of wing veins L4 and L5, and the frequency of ectopic bristle formation on the distal end of wing vein L3 (seen in pb^hs.PB heterozygotes) is increased to 90% for females and 50% for males. The enhancement of the pb^hs.PB antenna to maxillary transformation phenotype caused by Gap1^sxt-BJ61 is reduced if the flies also carry one copy of Ras85D^e1B. The enhancement of the Gap1^sxt-BJ61 ectopic wing vein phenotype caused by pb^hs.PB is reduced if the flies also carry one copy of Ras85D^e1B. The enhancement of the Df(3R)Ubx109/+ phenotype by Gap1^sxt-BJ61 is partially reversed if the flies also carry Ras85D^e1B.

(Boube et al., 1997)

Mutation has no effect on the rough eye phenotype caused by two insertions of P{GMR-Rho1}.

(Hariharan et al., 1995)

Enhances the sev^B4 phenotype: disrupts sev^B4 protein signalling.

(Simon et al., 1991)