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General Information
Symbol
Dmel\bab1P
Species
D. melanogaster
Name
FlyBase ID
FBal0030543
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
babP
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
P{A92} insertion close to the 5' end of the first intron of bab1. This results in aberrant splicing, with the 5' splice site of bab1 intron 1 and the 3' splice site of the l(3)87Df gene fragment which is present in the P{A92} insertion being spliced together. This produces a truncated 2.6kb transcript.
Insertion components
P{A92}bab1P
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Homozygous females have an intermediate mutant ovary phenotype; the females are semi-sterile to sterile and ovaries have an irregular shape and are substantially smaller than normal. The ovaries contains a reduced number of ovarioles that are abnormally oriented. Homozygotes have wild-type legs. Homozygous females show ectopic dark pigmentation in the A6 and A7 tergites.
Mutant females lay only a small number of eggs, many of which develop normally. Mutant ovaries are disorganized and smaller than wild type. The wild type pattern of parallel anterior-posterior oriented ovarioles is not apparent in the mutant ovary. A few chains of egg chambers are apparent, with abnormally small terminal filaments that have the form of a cluster rather than a stack. These terminal filaments are attached to abnormally shaped germaria from which egg chambers develop that are not well aligned in the anterior-posterior axis.
Semi-sterile in females.
Formation of terminal filaments is disrupted: severely disorganised adult ovaries.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
The P{A92}bab1P insertion does not affect the transcription of bab2.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (8)