The eyeless phenotype of eya2 adult mutants can be partially rescued by expression of soScer\UAS.FL.NT.T:Hsim\VP16 (but not soScer\UAS.cUa) under the control of Scer\GAL4ey.PU in the mutant background.
The no-eye phenotype of adult eya2 homozygous mutants can be fully rescued by combination with eyaRB.enh1+E+2 and partially restored by combination with any of the following: eyaRB.enh1, eyaRB.enhE, eyaRB.enh1+E or eyaRB.enh1+s+2 but cannot be rescued by any of these transgenes: eyaRB.enh2, eyaRB.enh3, eyaRB.enh4, eyaRB.enh1+2, eyaRB.enh1+5bp+2 and eyaRB.+535.+840.
One copy of either eya+tGR, eyaD493N.GR, eyaE728Q.GR or eyaNQ.GR rescues rescues eye formation in eya2 homozygotes. The external and internal morphology of the eyes is indistinguishable from wild type.
One copy of either eyaSA.GR or eyaSDE.GR rescues eye formation in eya2 homozygotes. The external morphology of the eyes are indistinguishable from wild type and cross sections show a normal number and arrangement of photoreceptors.
The posterior and lateral regions of the eye are rescued by eyaScer\UAS.cPa expressed under the control of Scer\GAL4dpp.blk1. The development of the neuronal array is rescued in the most posterior region of the eye disc by eyaScer\UAS.cPa expressed under the control of Scer\GAL4E132.