FB2020_01, released Feb 12, 2020

Allele: Dmel\eve1.27

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General Information
Symbol
Dmel\eve1.27
Species
D. melanogaster
Name
FlyBase ID
FBal0031219
Feature type
allele
Associated gene
Dmel\eve
Associated Insertion(s)
Carried in Construct
Allele class

loss of function allele

amorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - genetic evidence

    (Tremml and Bienz, 1989, DiNardo and O'Farrell, 1987)

    loss of function allele

    (Ingham and Hidalgo, 1993)
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
         
        Progenitor genotype
        Cytology
        Nature of the lesion
        Statement
        Reference
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        14% of eve1.27 homozygous embryos display defects in germ-band extension.

        (Bertet et al., 2009)

        Around 20% of eve1.27/+ first instar larvae have cuticular segmentation defects.

        (Bullock et al., 2004)

        Interacts with RpII140wimp maternal effect.

        (Parkhurst and Ish-Horowicz, 1991)

        Unsegmented 'lawn' phenotype of the cuticle. The arrays and patterns of mesodermal cells are disordered.

        (Tremml and Bienz, 1989)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhanced by
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The frequency of cuticular segmentation phenotypes in eve1.27/+ first instar larvae is significantly enhanced in animals with a egl3e/egl1 mutant mother.

        (Bullock et al., 2004)

        Sir205327a does not show a dominant synthetic lethal interaction with eve1.27.

        (Rosenberg and Parkhurst, 2002)

        Heterozygous progeny from RpL36/+ mothers show reduced viability. Heterozygous Kr or eve embryos derived from heterozygous l(2)41Ae34-4, Nipped-A1/+ females show increase in embryonic cuticular phenotypes.

        (Duffy et al., 1996)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        Df(3R)eve1.27
        (Tremml and Bienz, 1989)
        eve0
        (Azpiazu et al., 1996)
        eve1.27
        (Bertet et al., 2009)
        Name Synonyms
        Secondary FlyBase IDs
          References (19)