Only 27% of the expected number of fafFO8
zygotic mutants survive. The embryos have a ventralised cuticle with dorsally extended denticles and an ectopic denticle belt replacing the Filzkorper.
embryos have a ventralised cuticle with herniated head, dorsally extended denticles and an misplaced Filzkorper.
Embryos derived from fafB3
females mated to wild-type males show almost complete ventralisation of the cuticle. The rudimentary cuticle contains one anterior denticle belt that fully encircles the embryo.
Only 7% of embryos derived from fafB3
females form pole cells, and these embryos have far fewer pole cells than in wild-type embryos. The pole cells that form show a variety of migration defects, failing to migrate into the abdomen and instead spreading out over the embryo surface. Many of the embryos fail to undergo or undergo abnormal nuclear divisions; 45% of embryos derived from fafB3
females are unfertilised (one nucleus), 12% are arrested at a two nuclear stage and 40% are multinucleated, but usually have irregularly arranged nuclei.
Eyes roughened due to abnormalities in the hexagonal facet array: most facets include 1-3 extra outer photoreceptor cells which are probably mystery cells. Ovaries of homozygous females are normal in appearance but the embryos produced never form syncytial blastoderm and all fail to hatch.