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General Information
Symbol
Dmel\fafB6
Species
D. melanogaster
Name
FlyBase ID
FBal0031242
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:
G31780497A
Reported nucleotide change:
G?A
Amino acid change:
W459term | faf-PA; W459term | faf-PC; W459term | faf-PD; W459term | faf-PE; W459term | faf-PG; W459term | faf-PH; W459term | faf-PI
Reported amino acid change:
W459term
Comment:
TGG to TGA
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: W459term.
Nucleotide substitution: G?A.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Embryos derived from fafB4/fafB6 females mated to wild-type males show ventralisation of the cuticle, with a herniated head, defective Filzkorper and denticle belts that extend throughout the ventral half of the cuticle. Embryos derived from fafB6/Df(3R)faf-BP females mated to wild-type males show early embryonic lethality associated with blastoderm arrest and do not produce cuticle.
Eyes roughened due to abnormalities in the hexagonal facet array: but only 1% of facets are affected. Ovaries of homozygous females are normal in appearance but the embryos produced never form syncytial blastoderm and all fail to hatch.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)