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General Information
Symbol
Dmel\fafBX3
Species
D. melanogaster
Name
FlyBase ID
FBal0031251
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Polytene chromosomes normal.
Nature of the lesion
Statement
Reference
15bp deletion.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
ameliorates  epilepsy
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Embryos derived from fafB4/fafBX3 females mated to wild-type males show significant ventralisation of the cuticle, with a herniated head, defective Filzkorper, malformed dorsal cuticle and extended denticle belts.
fafBX3/fafFO8 eyes are nearly wild type.
fafBX3/fafFO8 flies have facets with more than the wild-type number of photoreceptor cell and an abnormal number of cone cells.
fafFO8/fafBX3 flies have essentially wild-type eyes.
fafBX3/fafFO8 and homozygous adults exhibit nearly wild type eyes with a smooth exterior.
Most facets of homozygotes and transheterozygotes with fafFO8 contain more than the normal complement of 8 photoreceptor cells, many facets have extra R7 cells and a small proportion have missing R7 cells.
Mutation causes no significant alteration to the variegated eye phenotype of In(1)wm4h.
Eyes roughened due to abnormalities in the hexagonal facet array: but only 1% of facets are affected. Ovaries of homozygous females are normal in appearance but the embryos produced never form syncytial blastoderm and all fail to hatch.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
fafFO8/fafBX3 has visible phenotype, enhanceable by shi[+]/shiEM45
fafFO8/fafBX3 has visible phenotype, enhanceable by shi1/shi1
fafFO8/fafBX3 has visible phenotype, enhanceable by shi2/shi2
fafBX3, lqfbE25 has visible | recessive phenotype, enhanceable by Chc[+]/Chc1
fafBX3, lqfbE25 has visible phenotype, enhanceable by Chc[+]/Chc1
fafFO8/fafBX3 has visible phenotype, enhanceable by lqfAG/lqf[+]
fafBX3, lqfbE25 has visible | recessive phenotype, enhanceable by Chc[+]/Chc4
fafBX3, lqfbE25 has visible phenotype, enhanceable by Chc[+]/Chc4
fafFO8/fafBX3 has visible phenotype, enhanceable by Chc[+]/Chc1
fafBX3 has visible phenotype, enhanceable by Chc4
fafFO8/fafBX3 has visible phenotype, enhanceable by shiEM42/shi[+]
Suppressed by
Statement
Reference
fafFO8/fafBX3, lqfbE25 has visible phenotype, suppressible by effXS347
fafFO8/fafBX3, lqfbE25 has visible phenotype, suppressible by eff01462
fafFO8/fafBX3, lqfbE25 has visible phenotype, suppressible by Prosβ61
Suppressor of
Statement
Reference
fafBX3/faf[+] is a suppressor of bang sensitive | dominant phenotype of pksple-1
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference
fafFO8/fafBX3 has eye phenotype, enhanceable by shi[+]/shiEM45
fafFO8/fafBX3 has eye phenotype, enhanceable by shi1/shi1
fafFO8/fafBX3 has eye phenotype, enhanceable by shi2/shi2
fafBX3, lqfbE25 has wing phenotype, enhanceable by Chc[+]/Chc1
fafBX3, lqfbE25 has eye phenotype, enhanceable by Chc[+]/Chc1
fafBX3, lqfbE25 has wing phenotype, enhanceable by Chc[+]/Chc4
fafBX3, lqfbE25 has eye phenotype, enhanceable by Chc[+]/Chc4
fafFO8/fafBX3 has eye phenotype, enhanceable by lqfAG/lqf[+]
fafFO8/fafBX3 has eye phenotype, enhanceable by Chc[+]/Chc1
fafFO8/fafBX3 has eye phenotype, enhanceable by shiEM42/shi[+]
fafBX3 has phenotype, enhanceable by Ras85DbE382
fafBX3 has phenotype, enhanceable by E(faf)bE160bE160
fafBX3 has phenotype, enhanceable by E(faf)bE184bE184
fafBX3 has phenotype, enhanceable by E(faf)bE184bE198
fafBX3 has phenotype, enhanceable by E(faf)bE184bE377
fafBX3 has phenotype, enhanceable by E(faf)bE184bE432
fafBX3 has phenotype, enhanceable by lqfbE248
fafBX3 has phenotype, enhanceable by E(faf)bE365bE365
fafBX3 has phenotype, enhanceable by lqfbE25
NOT Enhanced by
Statement
Reference
fafFO8/fafBX3 has ommatidium phenotype, non-enhanceable by arm1/arm[+]
fafFO8/fafBX3 has ommatidium phenotype, non-enhanceable by arm4/arm[+]
fafFO8/fafBX3 has ommatidium phenotype, non-enhanceable by cno3/cno[+]
fafFO8/fafBX3 has ommatidium phenotype, non-enhanceable by cno2/cno[+]
Suppressed by
Statement
Reference
fafFO8/fafBX3, lqfbE25 has ommatidium phenotype, suppressible by effXS347
fafFO8/fafBX3, lqfbE25 has ommatidium phenotype, suppressible by Prosβ61
fafFO8/fafBX3, lqfbE25 has ommatidium phenotype, suppressible by eff01462
Enhancer of
Statement
Reference
fafBX3 is an enhancer of eye photoreceptor cell phenotype of Rap1E8
fafBX3 is an enhancer of eye photoreceptor cell phenotype of Rap1E127
Other
Additional Comments
Genetic Interactions
Statement
Reference
The presence of fafBX3/+ rescues the bang-sensitive phenotype of pksple-1/+ mutants.
The eyes of fafBX3/fafFO8 flies are severely malformed if the flies are also carrying one copy of lqfAG. Nearly all facets of lqfbE25 fafBX3/fafBX3 eyes contain one or more ectopic photoreceptors in addition to the normal complement of 8. The fafBX3/fafFO8 phenotype is dominantly enhanced by Chc1, no enhancement if seen with Chc4. The fafBX3/fafFO8 phenotype is dominantly enhanced by shiEM42 or shiEM45. The fafBX3/fafFO8 phenotype is slightly enhanced if the flies are also homozygous for shi1 or shi2. The lqfbE25 fafBX3/fafBX3 mutant phenotype is dominantly enhanced by Chc1 or Chc4. The lqfbE25 fafBX3/fafFO8 mutant phenotype is suppressed by effXS347, eff01462, Pros26rv10e or Pros261.
The addition of three copies of P{ro-UbcD1.T:Hsap\MYC} to fafFO8/fafBX3 flies enhances the eye phenotype.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments
Weak allele.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)