Only 27% of the expected number of fafFO8
zygotic mutants survive. The embryos have a ventralised cuticle with dorsally extended denticles and an ectopic denticle belt replacing the Filzkorper.
embryos have a ventralised cuticle with dorsally extended denticles and poorly developed Filzkorper.
Embryos derived from fafB4
females mated to wild-type males show significant ventralisation of the cuticle, with a herniated head, defective Filzkorper, malformed dorsal cuticle and denticle belts that extend well into the dorsal half of the embryo.
homozygous somatic clones in the eye lead to the formation of ommatidia containing one additional photoreceptor cell. For an ommatidium to show this phenotype, it is sufficient for 2 of the photoreceptors R2 to R5 to be mutant.
The external surface of the eye is irregular in fafFO8
flies and most facets contain more than the wild-type number of photoreceptor cells.
flies have a rough eye phenotype, due to the ommatidia containing more than the normal number of photoreceptor cells. Embryos derived from homozygous females die prior to cellularisation. fafBX3
flies have facets with more than the wild-type number of photoreceptor cell and an abnormal number of cone cells.
Each facet contains more than the normal number of photoreceptors in mutant flies. BrdU incorporation resembles wild type in fafFO8
third larval instar eye discs.
adults exhibit nearly wild type eyes with a smooth exterior.
Most facets of transheterozygotes with fafBX3
contain more than the normal complement of 8 photoreceptor cells, many facets have extra R7 cells and a small proportion have missing R7 cells.
Mutation causes no significant alteration to the variegated eye phenotype of In(1)wm4h
Mutation has no effect on rhohs.sev
rough eye phenotype.
Eyes roughened due to abnormalities in the hexagonal facet array: most facets include 1-3 extra outer photoreceptor cells which are probably mystery cells. Ovaries of homozygous females are normal in appearance but the embryos produced never form syncytial blastoderm and all fail to hatch.