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General Information
Symbol
Dmel\hhb.PP
Species
D. melanogaster
Name
hunchback promoter construct of Parkhurst
FlyBase ID
FBal0031447
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hb-h
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Contains 6.5kb h genomic DNA, under the control of the hb promoter.

The hb promoter drives expression of the h coding region.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The lethality of females carrying hhb.PP is greater than 80%.

Causes female lethality (FBrf0051358).

More than 99% of hhb.PP females die as embryos, with head defects.

Females have defective mouthparts.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference

hhb.PP has lethal | female phenotype, non-enhanceable by evehb.PP

Suppressed by
Statement
Reference

hhb.PP has lethal | female phenotype, suppressible by ftzhb.PP

hhb.PP has lethal | female phenotype, suppressible by l(1)schb.PP

hhb.PP has lethal | female phenotype, suppressible by achb.PP

hhb.PP has lethal | female phenotype, suppressible by SxlM1

NOT suppressed by
Statement
Reference

hhb.PP has lethal | female phenotype, non-suppressible by ftzΔHD.hb

hhb.PP has lethal | female phenotype, non-suppressible by evehb.PP

Suppressor of
Statement
Reference

hhb.PP is a suppressor of lethal | female phenotype of schb.PP

hhb.PP is a suppressor of lethal | female phenotype of Xlae\hhb.PD

Other
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Ectopic h expression rescues schb.PP male lethality.

SxlM1 completely suppresses female lethality.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

hhb.PP partially rescues the pattern defects of mutant embryos deficient for h : mouthparts become more organised, and anterior structures including the maxillary sense organs and T1 denticle band are restored.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
hhb.PP
Name Synonyms
hunchback promoter construct of Parkhurst
Secondary FlyBase IDs
    References (8)