Open Close
General Information
Symbol
Dmel\hhs.P1
Species
D. melanogaster
Name
FlyBase ID
FBal0031448
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

h cDNA expression is driven by an Hsp70 promoter region including 250bp upstream of the start of transcription. The 3' end of the transcription unit derives from h.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ectopic expression of h does not affect cell number in the stalks between egg chambers.

Heat induced h expression causes two classes of cuticular patterns defects. One is 'pair-rule' embryos display pair-wise fusions of adjacent metameres. The second show more extreme deletions, in particular fusion of A2-A7 denticle bands to produce a 'lawn' embryo. The temperature sensitive period for each phenotype has been determined. Heat shock 5-20 minutes before gastrulation produces the pair-rule phenotype alone, 20-35 minutes before gastrulation produces the pair-rule and lawn phenotype and 35-50 minutes before gastrulation produces the lawn phenotype alone.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference

hhs.P1 is a suppressor of macrochaeta | ectopic phenotype of acHw-1

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Early pupae heat shocked for 1 hour at 36oC exhibit complete suppression of extra bristles on the L2 wing vein of h1 and h2 wings. The temperature sensitive period is day one of pupal development.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
hhs.P1
Name Synonyms
Secondary FlyBase IDs
    References (7)