hi22/+ first instar larvae only rarely have segmentation defects.
hi22/h674 embryos have salivary glands with either branched or expanded lumens.
Heterozygotes frequently have terminal incisions in the wing.
Transheterozygotes with hL43a are lethal, strong pair-rule phenotype.
Homozygous phenotype is variable. In some cases half the normal number of denticle bands form, due to a deletion of pattern elements from approximately the middle of one segment to a homologous position in the next segment ("pair-rule segmentation phenotype"). In other cases the deletions span more than one segment, resulting in the fusion of the compound segments. Weaker phenotypes are also seen, involving the formation of denticles corresponding to A2, A6 or both. Heterozygotes show some cuticle pattern defects.
Class IV allele: has a strong segmentation phenotype either when homozygous or in trans with h25, and fails to complement the bristle phenotype of h1. The denticle belts associated with the A3/4 and A5/6 composite segments are often fused in homozygous larvae.