hydhs1/hydC017 mutants exhibit abnormalities in spermatogenesis. One such abnormality is for nuclei scattered through the elongated cysts to exhibit a round shape instead of a 'needle' shape. In rare cases, the group of needle-shaped nuclei can be found in the correct place in the cyst; however, some of the nuclei are evidently incorrectly condensed. Approximately 90% of nuclei and micronuclei do not reach the correct cyst pole.
At 25oC homozygotes show hyperplastic imaginal disc overgrowth, affecting wing, haltere and eye-antennal discs, whereas at 18oC development proceeds normally. Mutant discs implanted into wild type hosts for metamorphosis overgrow and differentiate normal imaginal structures. Mutant larvae do not grow beyond the maximum size seen for wild type. A few escapers eclose as adults.
Imaginal discs show gap-junctional communication defects: coupling is severely diminished.