FB2025_01 , released February 20, 2025
Allele: Dmel\mtd4
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General Information
Symbol
Dmel\mtd4
Species
D. melanogaster
Name
FlyBase ID
FBal0031886
Feature type
allele
Associated gene
Dmel\mtd
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Carpenter, 1999, Carpenter, 1994)
Progenitor genotype
Caused by aberration
T(2;3)82Fd4
Cytology
Description

RFLP maps l(3)82Fd transcription unit.

(Stowers et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  autosomal recessive intellectual developmental disorder
      modeled by Nab2EP3716
      (Rounds et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous flies are eclosion lethals; flies assisted from their pupal cases are alive. Eye colour: wild type.

      (Carpenter, 1999)

      Shows developmental delay.

      (Stowers et al., 1999)

      Eclosion lethal.

      (Carpenter, 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      mtd[+]/mtd4 is a suppressor | partially of visible | adult stage phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)

      mtd[+]/mtd4 is a suppressor of abnormal eye color phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      mtd[+]/mtd4 is a suppressor | partially of eye phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      mtd4 is rescued by mtdhs.PS

      (Stowers et al., 1999)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A.T.C. Carpenter.

      (Carpenter, 1994)
      Comments
      Comments

      Alleles can be ranked on the basis of the length of time taken to reach eclosion. From most delayed (10-15 days) to least delayed (1-2 days): l(3)82Fd1 ~ l(3)82Fd2 > l(3)82Fd4 > l(3)82Fd7 > l(3)82Fd5 ~ l(3)82Fd8.

      (Stowers et al., 1999)

      The 82F puff does not puff in this mutant.

      (Carpenter, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(3)82Fd4
      mtd4
      (Rounds et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)