FB2025_01 , released February 20, 2025
Allele: Dmel\l(3)mbnE1
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General Information
Symbol
Dmel\l(3)mbnE1
Species
D. melanogaster
Name
FlyBase ID
FBal0032020
Feature type
allele
Associated gene
Dmel\l(3)mbn
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Becker et al., 1991)
Mutagen
ethyl methanesulfonate
(Konrad et al., 1994, Becker et al., 1991)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Konrad et al., 1994)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous and homozygous third instar larvae have melanotic nodules found in the hemocoel. In heterozygous larvae, the melanotic nodules are surrounded by lamellocytes.

      (Minakhina and Steward, 2006)

      Strong blood tumour phenotype.

      (Konrad et al., 1994)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      l(3)mbnE1/l(3)mbn[+] is an enhancer of wing margin phenotype of Bx2

      (Bronstein et al., 2010)
      Suppressor of
      Statement
      Reference

      l(3)mbnE1/l(3)mbn[+] is a suppressor of scutellar bristle | increased number phenotype of Chie5.5

      (Bronstein et al., 2010)

      l(3)mbnE1/l(3)mbn[+] is a suppressor of scutellar bristle | increased number phenotype of SsdpL7

      (Bronstein et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      E1
      (Bronstein et al., 2010)
      l(3)mbn-1E1
      (Konrad et al., 1994)
      l(3)mbnE1
      (Minakhina and Steward, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)