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General Information
Symbol
Dmel\oskCE4
Species
D. melanogaster
Name
FlyBase ID
FBal0032325
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    Somatic gonadal precursors (SGPs) are specified normally, but primordial germ cells are absent in embryos derived from oskCE4/osk8 females. The SGPs compact into spherical 'gonads' even in the absence of the germ cells.
    In embryos laid by osk8/oskCE4 mothers, compaction of somatic gonadal precursors in parasegment 10 (part of embryonic gonadal mesoderm) occurs normally, even though these embryos lack germ cells.
    The gonadal mesoderm coalesces normally in embryos derived from osk8/oskCE4 females, even though the embryos lack germ cells.
    Maternal effect phenotype when in trans with osk3.
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    NOT Suppressor of
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Embryos that are derived from oskCE4/osk8 females and are zygotically homozygous for enaC14-06 show defects or delays in somatic gonadal precursor cluster adhesion at stage 13 and fail to complete gonad compaction, resulting in extended or split gonads at later stages, as occurs in enaC14-06 single mutant embryos.
    The gonadal mesoderm fails to coalesce in foi20.71 oskCE4/foi16.33 embryos that are derived from osk mutant (foi20.71 oskCE4/osk8) females.
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    References (14)