Open Close
General Information
Symbol
Dmel\sdE3
Species
D. melanogaster
Name
FlyBase ID
FBal0032670
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a P{wE} element in an intron, approximately 5kb downstream of the transcription start site.

Insertion components
P{wE}sdE3
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The phenotypic expressivity of the sdE3 mutant phenotype is background dependent.

Homozygotes/hemizygotes have scalloped wings.

Heterozygotes show a direct effect on the shape of the wing, having an effect in the anterior region, but no effect in the posterior region.

Homozygotes and hemizygotes show a reduced response to 1mM sucrose in a proboscis extension test when stimulated on the tarsal or labellar sensilla. Adults also show a reduced response to sucrose, and a normal preference but increased tolerance for salt in a feeding preference assay. The L1 neuron shows a normal response on stimulation of the labellar taste hairs with varying concentrations of sucrose, NaCl or KCl. Larvae show a reduced avoidance of NaCl and KCl in a chemotaxis test. Adults and larvae show a normal response to benzaldehyde and iso-amyl acetate in olfactory assays.

Wing phenotype.

Similar wing phenotype to sd1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The ability of bimd653 to act as an enhancer of the sdE3 mutant phenotype is background dependent.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Hazelrigg.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (9)