shu2/shuPB70 females lay only approximately 30% as many eggs as wild-type females, none of which develop. Typically, the eggs are abnormally shaped and dorsal appendages, if present, are reduced or fused. The ovaries of these females contain at least 5 developing egg chambers in the majority of ovarioles. About 80% of the egg chambers contain the correct 15:1 ratio of nurse cells to oocyte but never develop to wild-type eggs. Although an oocyte is established, its identity is not maintained and the oocyte appears to fail in its further development, and the egg chambers degenerate. The oocyte is not correctly positioned in 5-10% of egg chambers and egg chambers are seen in which the oocyte appears polyploid (although not to the same extent as the nurse cells). Females containing homozygous germline clones lay abnormal eggs, which are similar to those laid by hemizygous females.
Few egg chambers, sometimes abnormal numbers of nurse cells, usually early degeneration, few small abnormal eggs.