Allele Dmel\stau^ry9

General Information
Symbol	Dmel\stau^ry9	Species	D. melanogaster
Name		FlyBase ID	FBal0032815
Feature type	allele	Associated gene	Dmel\stau

Map ( GBrowse )	Untitled Document
Allele class	loss of function allele
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	loss of function allele (Broadus et al., 1998)
Mutagen	P-element activity (St. Johnston et al., 1991)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:14,011,446..14,011,446 (St. Johnston et al., 1991, Sofola et al., 2007)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion into the first intron of stau. (St. Johnston et al., 1991)
Caused by insertion	P{ry11}stau^ry9 (St. Johnston et al., 1991, Sofola et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage \| maternal effect \| recessive (St. Johnston et al., 1991)
Phenotype Manifest In
	embryonic abdomen \| maternal effect (St. Johnston et al., 1991) embryonic head \| maternal effect (St. Johnston et al., 1991)
Detailed Description
	Statement Reference Glial development in the NGB 6-4T lineage is not affected in mutant embryos. (Freeman and Doe, 2001) Typical strong stau phenotype in which the head is reduced in size and is not involuted, and the abdomen in completely absent. (St. Johnston et al., 1991)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference stau^ry9 is an enhancer of neuroanatomy defective phenotype of Hsap\ATXN8OS^{CTG112.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Mutsuddi et al., 2004)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	10742 P{ry11}stau^ry9 cn¹/CyO; ry⁵⁰⁶
Notes on Origin
Discoverer	A. Spradling.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	fs(2)9 stau^ry9 Stau^ry9 (Sofola et al., 2007) stau^ry (Cha et al., 2001)
Name Synonym
Secondary FlyBase IDs

References ( 9 )
Research paper	Sofola et al., 2007, Neuron 55(4): 565--571 RNA-Binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. [FBrf0200897] Mutsuddi et al., 2004, Curr. Biol. 14(4): 302--308 The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila. [FBrf0174476] Mohr and Gelbart, 2002, Genetics 162(1): 165--176 Using the P{wHy} hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. [FBrf0152030] Cha et al., 2001, Cell 106(1): 35--46 In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway. [FBrf0137189] Freeman and Doe, 2001, Development 128(20): 4103--4112 Asymmetric Prospero localization is required to generate mixed neuronal/glial lineages in the Drosophila CNS. [FBrf0139636] Doane, 2000, D. I. S. 83: 168--170 Complementation tests using P-induced mutations place adipose in 55B. [FBrf0135619] Broadus et al., 1998, Nature 391(6669): 792--795 Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate. [FBrf0100537] St. Johnston et al., 1991, Cell 66(1): 51--63 staufen, a gene required to localize maternal RNAs in the Drosophila egg. [FBrf0053380] Spradling and Rubin, 1982, Science 218(4570): 341--347 Transposition of cloned P-elements into Drosophila germ line chromosomes. [FBrf0038719]

Allele Dmel\staury9

Allele Dmel\stau^ry9