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General Information
Symbol
Dmel\Syt1N6
Species
D. melanogaster
Name
FlyBase ID
FBal0032850
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Df(2L)N6
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Imprecise excision of the P{lacW} element, removing the 3' end of the P{lacW} element and the entire syt gene.

Imprecise excision of P-element from sytT77.

Deletion removing entire open reading frame of syt.

Insertion components
P{5'lacW}Syt1N6
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The average number of crystal cells per embryo is reduced in homozygous stage 13-14 embryos compared to wild type.

Growth cone advance and axonal pathfinding appear normal in homozygous embryos, and there is no delay in axonal outgrowth. The longitudinal tracts and commissures appear morphologically normal. The morphology of the neuromuscular junctions appears normal in stage 17 embryos.

Embryos show severe reduction in coordinated muscle contraction when compared with wild type, and an increase in uncoordinated twitching.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

The syt alleles form a series: going from most severe to least severe, sytN19 = sytN6 >= sytT7 = sytT41 > sytT77 = syt66.4 > sytT11.

Mutant phenotype cannot be rescued when homozygous by sytelav.PD.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (7)