Allele Dmel\tsh¹

General Information
Symbol	Dmel\tsh¹	Species	D. melanogaster
Name		FlyBase ID	FBal0032942
Feature type	allele	Associated gene	Dmel\tsh

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Fasano et al., 1991, Fasano et al., 1989, Rauskolb et al., 1995)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{A92}A (Fasano et al., 1989)
Nature of the lesion	Statement Reference P-element insertion into tsh. (Rauskolb et al., 1995) Insertion of P{A92} within the 5' flanking region of tsh. (Fasano et al., 1991)
Caused by insertion	P{A92}tsh¹ (Fasano et al., 1991, Rauskolb et al., 1995, Fasano et al., 1989)
Cytology
Phenotypic Data
Phenotypic Class
	lethal (Fasano et al., 1989) visible \| recessive (Fasano et al., 1991)
Phenotype Manifest In
	anterior scutellar bristle (Fasano et al., 1991) Keilin's organ (Fasano et al., 1989)
Detailed Description
	Statement Reference Homozygous viable, adults display a mild phenotype: twinning of the anterior scutellar bristles. Trans-heterozygotes with Df(2L)TW161 are semi-lethal: escapers have malformed prothoracic trochanters. Neuronal defects: disruption or deletion of ventral groups of neurons in the trunk region and misrouting of axons towards the head. (Fasano et al., 1991) Thorax sense organs are found adjacent to the malformed Keilins organs suggesting a partial transformation of the thoracic segments to the labial segment. (Fasano et al., 1989)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	tsh¹ tsh^R30b (Rauskolb et al., 1995)
Name Synonym
Secondary FlyBase IDs
	FBal0046623
References ( 3 )
Research paper	Rauskolb et al., 1995, Development 121(11): 3663--3673 Extradenticle determines segmental identities throughout Drosophila development. [FBrf0084293] Fasano et al., 1991, Cell 64: 63--79 The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc finger motifs. [FBrf0053386]
Abstract	Fasano et al., 1989, Europ. Dros. Res. Conf. 11: 241 A homeotic gene called teashirt. [FBrf0066382]

Allele Dmel\tsh1

Allele Dmel\tsh¹