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General Information
Symbol
Dmel\wblM46
Species
D. melanogaster
Name
FlyBase ID
FBal0033170
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
windM46
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C19250590T

Amino acid change:

Q188term | wbl-PA; Q188term | wbl-PB

Reported amino acid change:

Q188term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Single base change, resulting in the generation of a stop codon (UAG) after amino acid 187.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos derived from homozygous females are strongly dorsalised. Homozygous adults show reduced viability. Transheterozygotes with wblRP, wblM88, wblT6, wblE4 or wblAR51 also have reduced viability, and embryos derived from these transheterozygous females are dorsalised and fail to hatch.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

wblM46 has embryo | dorsal phenotype, suppressible by gdWT.cHa

Additional Comments
Genetic Interactions
Statement
Reference

Double mutant combinations with eaD3 are strongly dorsalized.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)