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General Information
Symbol
Dmel\wblT6
Species
D. melanogaster
Name
FlyBase ID
FBal0033173
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
windT6
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T19250744C

Amino acid change:

L239P | wbl-PA; L239P | wbl-PB

Reported amino acid change:

L239P

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: L239P.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

wblRP/wblT6 flies are smaller than wblT6/+ flies.

Embryos derived from homozygous females are strongly dorsalised. Homozygous adults show reduced viability, the lethal phase being between the second and third larval instar stages. Transheterozygotes with wblRP, wblM88, wblM46, wblE4 or wblAR51 also have reduced viability, and embryos derived from these transheterozygous females are dorsalised and fail to hatch.

Embryos transplanted with perivitelline fluid from Tl2 embryos exhibit a polar gastrulation. At the end of embryogenesis an almost complete restoration of pattern along the dorsoventral axis is seen. The point of injection determines the ventralmost point of the restored pattern.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

When piphs.PS is uniformly expressed in wblT6/wblRP females, the resulting embryos are dorsalised.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (5)