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General Information
Symbol
Dmel\y+ns
Species
D. melanogaster
Name
FlyBase ID
FBal0033195
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Contains a gypsy element at -700bp and a chimeric element at -69bp relative to the transcription start site. In the chimeric element, a 19.7kb sequence combined from three different X-chromosomal regions is flanked by two identical copies of a defective 1.2kb P-element which are oriented in the same way.

Insertion of a chimeric sequence flanked by deleted P-elements into the regulatory region of y.

22.1kb insertion 69bp upstream of the y transcription start site. y sequences from -146bp to -70bp are also deleted. The insertion contains a central region of 19.7kb genomic DNA flanked by two identical copies of a 1.2kb deleted P-element (nucleotides 830 to 2430 have been deleted and are replaced by a 10bp sequence), which are arranged in the same orientation. The direction of transcription of the P-elements is opposite to that of the y gene. Neither the whole insertion nor the individual P-elements are flanked by the characteristic base pair duplications that are normally found after P-element insertion. The 19.7kb genomic fragment that is flanked by the P-elements includes sequences from two, or possibly three, different regions of the X chromosome and some repetitive sequences. The gypsy element present in the progenitor y2 allele is still present.

Insertion components
gypsy{}y-2
P{}y+ns-b
P{}y+ns-a
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

macrochaeta & adult thorax

macrochaeta & leg

Detailed Description
Statement
Reference

Body colour: flies have wild-type pigmentation of the body and wings.

Body colour: body and wing wild-type; leg and thorax bristles reduced pigmentation.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

y+ns has adult cuticle & wing phenotype, enhanceable by su(Hw)2

y+ns has adult cuticle & wing phenotype, enhanceable by mod(mdg4)ul

y+ns has macrochaeta & leg phenotype, enhanceable by mod(mdg4)ul

y+ns has wing sensillum phenotype, enhanceable by mod(mdg4)ul

y+ns has macrochaeta & adult abdomen phenotype, enhanceable by mod(mdg4)ul

Additional Comments
Genetic Interactions
Statement
Reference

su(Hw)2 reduces body and wing pigmentation in y+ns males, but does not affect bristle pigmentation; mod(mdg4)ul partially decreases pigmentation of all cuticular structures in y+ns males.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Very unstable allele.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
y+ns
Name Synonyms
Secondary FlyBase IDs
    References (6)