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General Information
Symbol
Dmel\Axsr2
Species
D. melanogaster
Name
revertant 2
FlyBase ID
FBal0033471
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G16682002A

Reported nucleotide change:

G1489A

Amino acid change:

A223T | Axs-PA

Reported amino acid change:

A223T

Comment:

revertant of AxsD; see GB:AF101361.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: A223T.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Complete loss of the dominant phenotype: less than 2% X chromosome non-disjunction. Homozygotes show exactly the same meiotic phenotype as AxsD/+, namely high levels of X and fourth chromosome non-disjunction. Effect is limited to homologous achiasmate segregations. Nondisjunction is not accompanied by a significant level of chromosome loss. Axsr2/+ ncd1/+ females show much higher levels of both X and fourth chromosomal nondisjunction than do either of the single heterozygotes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Revertant.

Comments
Comments

Does not suppress AxsD in transheterozygotes. There is no evidence for second site noncomplementation between Axsr2 and ald1.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
revertant 2
Secondary FlyBase IDs
    References (3)