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General Information
Symbol
Dmel\Ada32
Species
D. melanogaster
Name
FlyBase ID
FBal0034849
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The dik protein truncates at amino acid 256.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The wing discs in homozygous dik2 third instar larvae are small compared to controls.

dik2 mutant cells are not recovered in germline clones, while twin control cell are recovered. No egg-producing ovarioles are recovered.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

Df(3L)iro-2, Ada32 has scutellum | heat sensitive phenotype, suppressible by araUAS.cGa/Scer\GAL4salm-AC216

Other
Statement
Reference

Df(3L)iro-2, Ada32 has scutellum | heat sensitive phenotype

Df(3L)iro-DFM1, Ada32 has scutellum | heat sensitive phenotype

Df(3L)iro-DFM3, Ada32 has scutellum | heat sensitive phenotype

Additional Comments
Genetic Interactions
Statement
Reference

80% of dik2 Df(3L)iro-2 double heterozygotes (dik2/+; Df(3L)iro-2/+ for females and dik2; Df(3L)iro-2/dik+tE4RX for males) display a phenotype that is characteristic of loss of the Iroquoi gene complex (IRO-C), which in around half of mutants appears as loss of the scutellum and several bristles from the remaining scutum in the thorax. The penetrance and expressivity of this phenotype are temperature sensitive, appearing stronger at 27[o]C than at 17[o]C. A similar phenotype is seen in flies heterozygous for dik2 and either Df(3L)iro-DFM1 or Df(3L)iro-DFM3.

Expression of araScer\UAS.cGa under the control of Scer\GAL4salm-AC216 completely suppresses the IRO-C phenotypes seen in dik2/+; Df(3L)iro-2/+ mutant flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Mutation in the haplo-lethal (HL) region of the Sh complex.

Mutation within the haplo-lethal (HL) region of the Sh complex.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Ada32
dik2
l(1)16Fh7688
Name Synonyms
Secondary FlyBase IDs
    References (4)