A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Dmel\l(2)k04301ak04301a

General Information
SymbolDmel\l(2)k04301ak04301aSpeciesD. melanogaster
NameFlyBase IDFBal0035082
Feature typealleleCreated / Updated2006-05-14/2006-05-14
Associated geneDmel\l(2)k04301a
Allele class
MutagenP-element activity
hide Nature of the Allele
Allele class
Mutagen
P-element activity
(Torok et al., 1993, Roch et al., 1998)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
       
       
      Assay mode
      Caused by insertion
      P{lacW}l(2)k04301ak04301a
      (Torok et al., 1993, BDGP Project Members, 1994-1999, Spradling et al., 1999, Roch et al., 1998)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      lethal | recessive
      (Roch et al., 1998, Spradling et al., 1999)
      lethal | pupal stage
      (Torok et al., 1993)
      hyperplastic
      (Torok et al., 1993)
      hide Phenotype Manifest In
      larval brain
      (Torok et al., 1993)
      ventral prothoracic disc
      (Torok et al., 1993)
      ventral mesothoracic disc
      (Torok et al., 1993)
      ventral metathoracic disc
      (Torok et al., 1993)
      hide Detailed Description
      Statement
      Reference
      Brain occasionally shows outgrowths, hyperplastic outgrowth of leg discs and folding of all discs is abnormal after day 4.
      (Torok et al., 1993)
      Lethality occurs during third instar larval or pupal stages. Mutants do not show any visible disc abnormalities.
      (Roch et al., 1998)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Fails to complement
      l(2)k04301ak00202a
      (BDGP Project Members, 1994-1999)
      Comments
      hide Stocks ( 0 )
      hide Notes on Origin
      Discoverer
      hide Comments
      P-element excision demonstrates the insertion to be the cause of lethality.
      (Torok et al., 1993)
      Complements: l(2)00434a00434a. Complements: wg02657. Complements: cuc03264a. Complements: l(2)k10113k10113. Complements: wgrO505.
      (BDGP Project Members, 1994-1999)
      hide Synonyms & Secondary IDs ( 4 )
      Reported As
      Symbol Synonym
      43/1
      (Roch et al., 1998)
      l(2)k04301k04301
       
      l(2)k04301a
      (Spradling et al., 1999)
      l(2)k04301ak04301a
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 5 )
        Research paper
        Spradling et al., 1999, Genetics 153(1): 135--177
        The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
        Roch et al., 1998, Molec. gen. Genet. 257(2): 103--112
        Screening of larval/pupal P-element induced lethals on the second chromosome in Drosophila melanogaster: clonal analysis and morphology of imaginal discs. [FBrf0100624]
        Torok et al., 1993, Genetics 135(1): 71--80
        P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. [FBrf0058618]
        Personal communication to FlyBase
        Beaton, 1999.12.12, Alleles of the lines in the P-element paper.
        Alleles of the lines in the P-element paper. [FBrf0125032]
        Computer file
        BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project.
        Berkeley Drosophila Genome Project. [FBrf0067338]