Allele Dmel\l(2)k08634^k08634

General Information
Symbol	Dmel\l(2)k08634^k08634	Species	D. melanogaster
Name		FlyBase ID	FBal0035086
Feature type	allele	Created / Updated	2006-05-14/2006-05-14
Associated gene	Dmel\l(2)k08634

Allele class
Mutagen	P-element activity
Nature of the Allele
Allele class
Mutagen	P-element activity (Torok et al., 1993)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Assay mode
Caused by insertion	P{lacW}l(2)k08634^k08634 (Torok et al., 1993, BDGP Project Members, 1994-1999)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| larval stage (Torok et al., 1993)
Phenotype Manifest In
	larval brain (Torok et al., 1993) lymph gland (Torok et al., 1993)
Detailed Description
	Statement Reference Brain and discs are smaller than wild type. Lymph glands retain lobular structure. Melanotic stripes appear in the larval cuticle before death, infrequent melanotic masses in larvae. (Torok et al., 1993)
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Kyoto	102658 Df(1)w67c23, y¹ ; P{lacW}l(2)k08634^k08634 / CyO
Notes on Origin
Discoverer

Comments
	This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu). P-element excision demonstrates the insertion to be the cause of lethality. (Torok et al., 1993)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	l(2)k08634 (Savant-Bhonsale et al., 1999) l(2)k08634^k08634
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Savant-Bhonsale et al., 1999, Gene 231(1-2): 155--161 A Drosophila derailed homolog, doughnut, expressed in invaginating cells during embryogenesis. [FBrf0108470] Torok et al., 1993, Genetics 135(1): 71--80 P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. [FBrf0058618]
Computer file	BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Allele Dmel\l(2)k08634k08634

Allele Dmel\l(2)k08634^k08634