Allele Dmel\Oda^k13107

General Information
Symbol	Dmel\Oda^k13107	Species	D. melanogaster
Name		FlyBase ID	FBal0035089
Feature type	allele	Created / Updated	2006-05-14/2006-05-14
Associated gene	Dmel\Oda

Allele class
Mutagen	P-element activity
Nature of the Allele
Allele class
Mutagen	P-element activity (BDGP Project Members, 1994-1999, Schenkel et al., 2002)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference P{lacW} insertion within an intron of Oda. (Schenkel et al., 2002)
Assay mode
Caused by insertion	P{lacW}SmD3^k13107 (Torok et al., 1993, BDGP Project Members, 1994-1999, Schenkel et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu). The level of SmD3 transcript is strongly reduced in P{lacW}SmD3^k13107 homozygotes compared to wild type, whereas Oda expression remains essentially unaffected. The level of SmD3 protein is lowered compared to wild type in P{lacW}SmD3^k13107/+ larvae and strongly reduced in P{lacW}SmD3^k13107 homozygous larvae. The P{lacW}SmD3^k13107 insertion appears to affect only SmD3 function and not Oda function (despite being within an Oda intron), since the lethality of P{lacW}SmD3^k13107 homozygotes is fully rescued by the P{SmD3.+t2.3} construct which contains the complete SmD3 gene. (Schenkel et al., 2002)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	guf^k13107 l(2)k09037^k13107 Oda^k13107
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Schenkel et al., 2002, Genetics 161(2): 763--772 P elements inserted in the vicinity of or within the Drosophila snRNP SmD3 gene nested in the first intron of the Ornithine decarboxylase antizyme gene affect only the expression of SmD3. [FBrf0149027] Torok et al., 1993, Genetics 135(1): 71--80 P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. [FBrf0058618]
Computer file	BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]

Allele Dmel\Odak13107

Allele Dmel\Oda^k13107