|Feature type||allele||Associated gene||Dmel\pnt|
|Map ( GBrowse )||
|Allele class||hypomorphic allele - genetic evidence|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Caused by insertion|
|Phenotype Manifest In|
Many pnt[Δ88]/pnt ommatidia over- or under-rotate; the variance (s.d.) in degree of rotation is greater than in wild type in adult eyes.
pnt/pnt eye discs show polarity defects (10% of ommatidial clusters are inverted and 9% are symmetrical). pnt/pnt[Δ88] eye discs show polarity defects (6.7% of ommatidial clusters are inverted and 6% are symmetrical).
pnt1277/pntΔ88 flies display a weak rough eye phenotype but pnt1277/pnt07825 flies have normal eyes.
In pnt1277/pntΔ88 mutant adults defects are seen in the eye. Under-recruitment of phtoreceptors is common, though in those ommatidia that are correctly specified, mis-rotations are seen.
90% of the ommatidia in pntΔ88/pnt1277 flies lack the R7 photoreceptor and/or some outer photoreceptor cells.
|Phenotype Manifest In|
pnt1277/pntΔ88 has eye photoreceptor cell phenotype, enhanceable by Scer\GAL4elav.PU/Bap170C1.Scer\UAS
pnt1277 has eye photoreceptor cell phenotype, suppressible | partially by ALV\v-etsScer\UAS.cAa/Scer\GAL4hs.2sev
pnt1277/pnt07825 is an enhancer of ommatidium phenotype of GugScer\UAS.cCa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Bap170[hfl1]/+ suppresses the loss of photoreceptor cells seen in pnt[Δ88]/pnt flies. Expression of Bap170[C1.Scer\UAS] under the control of Scer\GAL4[elav.PU] enhances the rough eye phenotype and loss of photoreceptor cells seen in pnt[Δ88]/pnt flies.
ed[1X5] dominantly enhances the phenotype of mis-rotation of ommatidia that is seen in pnt[Δ88]/pnt animals. fred[H24] dominantly suppresses the phenotype of mis-rotation of ommatidia that is seen in pnt[Δ88]/pnt animals.
The rough eye phenotype of flies expressing GugScer\UAS.cCa under the control of Scer\GAL4GMR.PF is enhanced in both a pnt1277/pntΔ88 and a pnt1277/pnt07825 background.
The extra outer photoreceptor cell phenotype seen in fafBX4 homozygotes is suppressed by pnt1277, with the average number of outer photoreceptor cells per ommatidium being reduced to 6.2.
|Complementation & Rescue Data|
|Partially rescued by|
The eye phenotype of pntΔ88/pnt1277 flies is partially rescued when pntP1.Scer\UAS is expressed using Scer\GAL4hs.2sev at 17oC.
|Stocks ( 1 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 1 )|
|Secondary FlyBase IDs|
|References ( 13 )|