|Feature type||allele||Associated gene||Dmel\ptc|
|Allele class||amorphic allele - genetic evidence|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Caused by insertion|
|Phenotype Manifest In|
ptctuf-1/ptcH84 flies have mildly reduced eyes but a highly enlarged head vertex. 90% of these flies have outgrowths of head cuticle and large numbers of missing, misplaced or ectopic head bristles with the remaining 10% having no outgrowths and one or 2 displaced or missing bristles. ptc559.1/ptcH84 flies have normal sized eyes and head vertex and a low incidence of ectopic or misplaced head bristles.
100% of ptchdl embryos transheterozygous with ptcH84 show head capsule defects. 4% of ptcH84/ptc559.1 transheterozygotes show head capsule defects.
An NB 7-3-like fate is formed ectopically in 50% of mutant hemineuromeres. 60% of EL cells are missing.
30% hemisegments exhibit failure of neuroblast NB4-2 to delaminate from the neuroectoderm.
|Phenotype Manifest In|
|NOT suppressed by|
The addition of smo1 to ptcH84/ptc559.1 animals produces an enhancement of the head capsule defect phenotype. 35% of animals exhibit the phenotype, compared to 4%. The addition of smo1 to ptcH84/ptchdl animals has no effect on the head capsule defect phenotype. All animals continue to show the phenotype. 2% of ptcH84, smo1/+ animals show a head capsule defect. 5% of babo32, ptcH84 double heterozygotes exhibit head capsule defects. 10% of ptcH84, smo1/+, babok07737 animals exhibit head capsule defects. No ptcH84, put10460 animals exhibit head capsule defects. The addition of Df(3L)H99 of ptcH84/ptchdl does not suppress head capsule defects. The addition of baboQ302D.Scer\UAS (driven by Scer\GAL469B) suppresses the head capsule defect phenotype seen in ptcH84/ptchdl. None of these animals exhibit head capsule defects.
|Complementation & Rescue Data|
|Fails to complement|
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 3 )|
|Secondary FlyBase IDs|
|References ( 11 )|