Allele Dmel\spz^C-106

General Information
Symbol	Dmel\spz^C-106	Species	D. melanogaster
Name		FlyBase ID	FBal0035679
Feature type	allele	Associated gene	Dmel\spz

Allele class
Mutagen	in vitro construct - deletion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Morisato and Anderson, 1994)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: N terminal deletion, beginning at base pair 1306, leaving the C terminal 106 amino acids. (Morisato and Anderson, 1994)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Embryos derived from spz⁴/Df(3R)Bd mothers become lateralized when injected with spz^C-106 transcripts. The same pattern results when dorsalized ea mutant embryos are injected, indicating that the requirement for ea has been bypassed. No rescue is observed if the embryos are laid by Tl or tub mothers. (Morisato and Anderson, 1994)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Carried in a plasmid, used to generate transcripts for RNA injection assays. (Morisato and Anderson, 1994)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	spz^C-106
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Zhou et al., 2005, J. Biol. Chem. 280(40): 34048--34055 The role of ubiquitination in Drosophila innate immunity. [FBrf0190911] Tauszig et al., 2000, Proc. Natl. Acad. Sci. U.S.A. 97(19): 10520--10525 From the cover: toll-related receptors and the control of antimicrobial peptide expression in Drosophila. [FBrf0130108] Morisato and Anderson, 1994, Cell 76(4): 677--688 The spatzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo. [FBrf0068603]

Allele Dmel\spzC-106

Allele Dmel\spz^C-106